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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DICER1
All Species:
11.21
Human Site:
S1426
Identified Species:
18.97
UniProt:
Q9UPY3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPY3
NP_085124.2
1922
218682
S1426
E
E
D
E
E
E
E
S
L
M
W
R
A
P
K
Chimpanzee
Pan troglodytes
XP_001154199
1922
218702
S1426
E
E
D
E
E
E
E
S
L
M
W
R
A
P
K
Rhesus Macaque
Macaca mulatta
XP_001100868
1920
218494
S1424
E
E
D
E
E
E
E
S
L
M
W
R
A
P
K
Dog
Lupus familis
XP_537547
1923
218622
D1427
E
D
D
E
E
E
E
D
L
M
W
R
A
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R418
1916
216802
R1426
E
E
E
D
L
T
W
R
A
P
K
E
E
A
E
Rat
Rattus norvegicus
XP_001068155
1918
216871
A1426
E
E
E
E
E
E
L
A
W
R
A
P
K
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510982
1921
218622
M1427
E
E
E
D
E
D
L
M
W
R
L
P
K
E
E
Chicken
Gallus gallus
Q25BN1
1921
218592
M1427
D
E
E
D
E
D
L
M
W
R
L
P
K
E
E
Frog
Xenopus laevis
NP_001163918
1795
204583
S1321
D
S
H
E
G
R
L
S
Y
M
R
S
K
K
V
Zebra Danio
Brachydanio rerio
Q6TV19
1865
210798
A1388
S
D
E
N
K
D
L
A
N
G
K
A
S
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCU9
2249
255312
D1630
V
L
A
K
K
L
G
D
R
R
E
L
L
L
S
Honey Bee
Apis mellifera
NP_001116485
1946
224489
T1425
S
L
I
L
Q
A
L
T
M
S
N
A
N
D
G
Nematode Worm
Caenorhab. elegans
P34529
1845
210905
N1340
L
T
A
L
T
T
S
N
A
A
D
G
M
S
L
Sea Urchin
Strong. purpuratus
XP_790894
1850
210427
A1360
Y
C
L
G
D
K
K
A
L
A
H
K
M
Q
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.3
97
N.A.
93
93.5
N.A.
91.8
92
76.5
79.2
N.A.
27.7
35.8
31.7
43.5
Protein Similarity:
100
99.9
99.7
98.4
N.A.
96.1
96.4
N.A.
95.8
95.9
83.9
85.5
N.A.
44
54.5
49.6
60.7
P-Site Identity:
100
100
100
86.6
N.A.
13.3
33.3
N.A.
20
13.3
20
0
N.A.
0
0
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
33.3
53.3
N.A.
46.6
46.6
26.6
40
N.A.
13.3
20
6.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
8
0
22
15
15
8
15
29
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
15
29
22
8
22
0
15
0
0
8
0
0
15
8
% D
% Glu:
50
50
36
43
50
36
29
0
0
0
8
8
8
22
29
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
8
0
0
8
0
8
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
15
8
8
0
0
0
15
8
29
8
29
% K
% Leu:
8
15
8
15
8
8
43
0
36
0
15
8
8
8
8
% L
% Met:
0
0
0
0
0
0
0
15
8
36
0
0
15
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
8
0
8
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
22
0
29
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
0
8
8
29
8
29
0
0
0
% R
% Ser:
15
8
0
0
0
0
8
29
0
8
0
8
8
8
8
% S
% Thr:
0
8
0
0
8
15
0
8
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
8
0
22
0
29
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _