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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DICER1 All Species: 32.42
Human Site: S1344 Identified Species: 54.87
UniProt: Q9UPY3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPY3 NP_085124.2 1922 218682 S1344 D A H E G R L S Y M R S K K V
Chimpanzee Pan troglodytes XP_001154199 1922 218702 S1344 D A H E G R L S Y M R S K K V
Rhesus Macaque Macaca mulatta XP_001100868 1920 218494 S1342 D A H E G R L S Y M R S K K V
Dog Lupus familis XP_537547 1923 218622 S1345 D A H E G R L S Y M R S K K V
Cat Felis silvestris
Mouse Mus musculus Q8R418 1916 216802 S1344 D A H E G R L S Y M R S K K V
Rat Rattus norvegicus XP_001068155 1918 216871 S1344 D A H E G R L S Y M R S K K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510982 1921 218622 S1345 D A H E G R L S Y M R S K K V
Chicken Gallus gallus Q25BN1 1921 218592 S1345 D A H E G R L S Y M R S K K V
Frog Xenopus laevis NP_001163918 1795 204583 P1239 L D G N V G K P I S D E C P S
Zebra Danio Brachydanio rerio Q6TV19 1865 210798 K1306 M L G D S F L K H A I T T Y L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCU9 2249 255312 L1548 Q Y Q Q T K N L L I G F N F K
Honey Bee Apis mellifera NP_001116485 1946 224489 T1343 K I V I K R K T S F S L H S E
Nematode Worm Caenorhab. elegans P34529 1845 210905 G1258 E I E E L S I G A R K K Q E I
Sea Urchin Strong. purpuratus XP_790894 1850 210427 D1278 G N F H L D D D G K D P Q M C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.3 97 N.A. 93 93.5 N.A. 91.8 92 76.5 79.2 N.A. 27.7 35.8 31.7 43.5
Protein Similarity: 100 99.9 99.7 98.4 N.A. 96.1 96.4 N.A. 95.8 95.9 83.9 85.5 N.A. 44 54.5 49.6 60.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 0 6.6 N.A. 0 6.6 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 0 33.3 N.A. 20 13.3 46.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 58 0 0 0 0 0 0 8 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % C
% Asp: 58 8 0 8 0 8 8 8 0 0 15 0 0 0 0 % D
% Glu: 8 0 8 65 0 0 0 0 0 0 0 8 0 8 8 % E
% Phe: 0 0 8 0 0 8 0 0 0 8 0 8 0 8 0 % F
% Gly: 8 0 15 0 58 8 0 8 8 0 8 0 0 0 0 % G
% His: 0 0 58 8 0 0 0 0 8 0 0 0 8 0 0 % H
% Ile: 0 15 0 8 0 0 8 0 8 8 8 0 0 0 8 % I
% Lys: 8 0 0 0 8 8 15 8 0 8 8 8 58 58 8 % K
% Leu: 8 8 0 0 15 0 65 8 8 0 0 8 0 0 8 % L
% Met: 8 0 0 0 0 0 0 0 0 58 0 0 0 8 0 % M
% Asn: 0 8 0 8 0 0 8 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 8 0 8 0 % P
% Gln: 8 0 8 8 0 0 0 0 0 0 0 0 15 0 0 % Q
% Arg: 0 0 0 0 0 65 0 0 0 8 58 0 0 0 0 % R
% Ser: 0 0 0 0 8 8 0 58 8 8 8 58 0 8 8 % S
% Thr: 0 0 0 0 8 0 0 8 0 0 0 8 8 0 0 % T
% Val: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 58 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 58 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _