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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHANK2
All Species:
13.33
Human Site:
Y538
Identified Species:
29.33
UniProt:
Q9UPX8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPX8
NP_036441.2
1470
158822
Y538
K
S
P
T
P
R
V
Y
G
T
I
K
P
A
F
Chimpanzee
Pan troglodytes
XP_001174048
1254
134901
K385
P
Q
A
N
F
R
N
K
R
G
Q
M
P
E
N
Rhesus Macaque
Macaca mulatta
XP_001099714
1248
134508
R380
Q
A
N
F
R
N
K
R
G
Q
M
P
E
N
P
Dog
Lupus familis
XP_540798
1938
209283
G913
E
K
S
G
N
K
T
G
S
C
H
E
G
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80Z38
1476
158961
Y542
R
S
P
T
P
R
V
Y
G
T
I
K
P
A
F
Rat
Rattus norvegicus
Q9QX74
1474
158665
Y543
R
S
P
T
P
R
V
Y
G
T
I
K
P
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507367
1367
148107
G495
P
N
F
R
N
K
R
G
Q
M
P
E
N
P
Y
Chicken
Gallus gallus
XP_426415
1770
194380
Y835
K
S
P
T
S
R
S
Y
G
T
I
K
P
P
F
Frog
Xenopus laevis
Q52KW0
1292
141161
S424
E
L
Y
N
S
N
M
S
T
Q
Q
N
F
I
N
Zebra Danio
Brachydanio rerio
NP_001121819
1800
196374
I894
A
G
R
G
Y
G
T
I
R
A
G
F
T
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786852
1022
110132
E154
F
P
A
L
Q
Y
L
E
H
V
D
K
G
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.1
83.6
62.3
N.A.
88.7
89.2
N.A.
77
64.8
62.2
48.4
N.A.
N.A.
N.A.
N.A.
23.2
Protein Similarity:
100
84.8
84
67
N.A.
93.1
93.4
N.A.
82.8
71.5
71.4
58.9
N.A.
N.A.
N.A.
N.A.
38.9
P-Site Identity:
100
13.3
6.6
0
N.A.
93.3
93.3
N.A.
0
80
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
26.6
20
N.A.
100
100
N.A.
26.6
80
13.3
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
19
0
0
0
0
0
0
10
0
0
0
28
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
19
0
0
0
0
0
0
10
0
0
0
19
10
10
0
% E
% Phe:
10
0
10
10
10
0
0
0
0
0
0
10
10
0
37
% F
% Gly:
0
10
0
19
0
10
0
19
46
10
10
0
19
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
37
0
0
10
0
% I
% Lys:
19
10
0
0
0
19
10
10
0
0
0
46
0
10
0
% K
% Leu:
0
10
0
10
0
0
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
10
10
10
0
0
0
% M
% Asn:
0
10
10
19
19
19
10
0
0
0
0
10
10
10
19
% N
% Pro:
19
10
37
0
28
0
0
0
0
0
10
10
46
19
19
% P
% Gln:
10
10
0
0
10
0
0
0
10
19
19
0
0
0
10
% Q
% Arg:
19
0
10
10
10
46
10
10
19
0
0
0
0
0
0
% R
% Ser:
0
37
10
0
19
0
10
10
10
0
0
0
0
19
0
% S
% Thr:
0
0
0
37
0
0
19
0
10
37
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
28
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
10
0
37
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _