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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHANK2
All Species:
13.03
Human Site:
S523
Identified Species:
28.67
UniProt:
Q9UPX8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPX8
NP_036441.2
1470
158822
S523
P
P
S
P
P
P
P
S
P
T
T
Y
N
C
P
Chimpanzee
Pan troglodytes
XP_001174048
1254
134901
D370
R
Y
S
L
D
S
E
D
L
Y
S
R
N
A
G
Rhesus Macaque
Macaca mulatta
XP_001099714
1248
134508
L365
Y
S
L
D
S
E
D
L
Y
S
R
N
A
G
P
Dog
Lupus familis
XP_540798
1938
209283
A898
S
S
Q
G
S
A
N
A
F
E
S
S
G
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80Z38
1476
158961
S527
P
P
S
P
P
P
P
S
P
T
T
Y
N
C
P
Rat
Rattus norvegicus
Q9QX74
1474
158665
S528
P
P
S
P
P
P
P
S
P
T
T
Y
N
C
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507367
1367
148107
Y480
S
L
D
S
E
D
L
Y
N
R
N
A
A
A
Q
Chicken
Gallus gallus
XP_426415
1770
194380
S820
P
P
S
P
P
P
P
S
P
S
L
Y
N
A
P
Frog
Xenopus laevis
Q52KW0
1292
141161
N409
M
Y
F
R
H
E
A
N
R
F
S
L
D
S
E
Zebra Danio
Brachydanio rerio
NP_001121819
1800
196374
P879
A
I
S
P
P
S
P
P
H
N
N
A
P
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786852
1022
110132
V139
K
S
P
Q
G
G
A
V
S
F
T
P
T
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.1
83.6
62.3
N.A.
88.7
89.2
N.A.
77
64.8
62.2
48.4
N.A.
N.A.
N.A.
N.A.
23.2
Protein Similarity:
100
84.8
84
67
N.A.
93.1
93.4
N.A.
82.8
71.5
71.4
58.9
N.A.
N.A.
N.A.
N.A.
38.9
P-Site Identity:
100
13.3
6.6
6.6
N.A.
100
100
N.A.
0
80
0
33.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
13.3
20
N.A.
100
100
N.A.
0
86.6
20
33.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
19
10
0
0
0
19
19
28
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
28
0
% C
% Asp:
0
0
10
10
10
10
10
10
0
0
0
0
10
0
10
% D
% Glu:
0
0
0
0
10
19
10
0
0
10
0
0
0
0
10
% E
% Phe:
0
0
10
0
0
0
0
0
10
19
0
0
0
0
0
% F
% Gly:
0
0
0
10
10
10
0
0
0
0
0
0
10
19
10
% G
% His:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
10
10
10
0
0
10
10
10
0
10
10
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
10
10
10
19
10
46
0
0
% N
% Pro:
37
37
10
46
46
37
46
10
37
0
0
10
10
0
64
% P
% Gln:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
0
0
10
0
0
0
0
10
10
10
10
0
0
0
% R
% Ser:
19
28
55
10
19
19
0
37
10
19
28
10
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
28
37
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
19
0
0
0
0
0
10
10
10
0
37
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _