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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHANK2
All Species:
22.12
Human Site:
S1129
Identified Species:
48.67
UniProt:
Q9UPX8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPX8
NP_036441.2
1470
158822
S1129
D
H
H
L
E
T
T
S
T
I
S
T
V
S
S
Chimpanzee
Pan troglodytes
XP_001174048
1254
134901
A943
T
V
Y
A
D
G
Q
A
F
M
V
D
K
P
P
Rhesus Macaque
Macaca mulatta
XP_001099714
1248
134508
A937
T
V
Y
A
D
G
Q
A
F
M
V
D
K
P
P
Dog
Lupus familis
XP_540798
1938
209283
S1596
D
H
H
L
E
T
T
S
T
I
S
T
V
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80Z38
1476
158961
S1133
D
H
H
L
E
T
T
S
T
I
S
T
V
S
S
Rat
Rattus norvegicus
Q9QX74
1474
158665
S1133
D
H
H
L
E
T
T
S
T
I
S
T
V
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507367
1367
148107
A1056
T
V
Y
A
D
G
Q
A
F
M
V
D
K
P
P
Chicken
Gallus gallus
XP_426415
1770
194380
S1428
D
H
H
L
E
T
T
S
T
I
S
T
V
S
S
Frog
Xenopus laevis
Q52KW0
1292
141161
A981
L
D
T
C
T
V
Y
A
D
G
Q
A
F
L
V
Zebra Danio
Brachydanio rerio
NP_001121819
1800
196374
S1480
D
P
Q
L
E
T
T
S
T
I
S
T
V
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786852
1022
110132
K711
A
A
S
A
M
Q
N
K
I
A
S
R
P
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.1
83.6
62.3
N.A.
88.7
89.2
N.A.
77
64.8
62.2
48.4
N.A.
N.A.
N.A.
N.A.
23.2
Protein Similarity:
100
84.8
84
67
N.A.
93.1
93.4
N.A.
82.8
71.5
71.4
58.9
N.A.
N.A.
N.A.
N.A.
38.9
P-Site Identity:
100
0
0
100
N.A.
100
100
N.A.
0
100
0
86.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
26.6
100
N.A.
100
100
N.A.
26.6
100
6.6
86.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
37
0
0
0
37
0
10
0
10
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
55
10
0
0
28
0
0
0
10
0
0
28
0
0
0
% D
% Glu:
0
0
0
0
55
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
28
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
28
0
0
0
10
0
0
0
0
0
% G
% His:
0
46
46
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
55
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
28
0
0
% K
% Leu:
10
0
0
55
0
0
0
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
10
0
0
0
0
28
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
0
10
37
28
% P
% Gln:
0
0
10
0
0
10
28
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
55
0
0
64
0
0
55
55
% S
% Thr:
28
0
10
0
10
55
55
0
55
0
0
55
0
0
0
% T
% Val:
0
28
0
0
0
10
0
0
0
0
28
0
55
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
28
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _