KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
13.33
Human Site:
Y849
Identified Species:
22.56
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
Y849
P
S
V
P
P
P
G
Y
M
P
R
Q
E
D
P
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
L771
V
S
G
E
E
A
R
L
P
P
R
E
E
A
E
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
Dog
Lupus familis
XP_543382
1925
209302
Y852
P
S
V
P
P
P
G
Y
V
P
R
Q
E
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
Y840
P
S
V
P
P
P
G
Y
I
P
R
Q
E
D
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
Chicken
Gallus gallus
Q5F3P8
2008
223067
Y834
P
S
V
P
P
P
G
Y
E
P
K
K
E
D
P
Frog
Xenopus laevis
Q66J90
1938
216239
K807
P
K
K
E
D
P
H
K
A
T
V
D
G
V
L
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
N811
A
I
M
K
K
D
L
N
R
K
M
V
E
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
I727
R
Q
K
V
K
Q
V
I
G
Y
I
V
E
E
L
Honey Bee
Apis mellifera
XP_395451
1406
159180
A493
T
S
Q
L
Y
P
G
A
G
Y
P
G
H
L
T
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
P594
P
P
Q
H
M
A
P
P
P
I
T
T
S
L
P
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
W821
Y
M
K
Q
E
E
Q
W
G
R
Y
R
Q
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
K400
A
L
M
E
A
V
L
K
K
S
R
E
T
S
Q
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
26.6
0
93.3
N.A.
93.3
N.A.
N.A.
0
80
13.3
6.6
N.A.
6.6
20
13.3
0
P-Site Similarity:
100
33.3
0
100
N.A.
100
N.A.
N.A.
0
93.3
13.3
13.3
N.A.
13.3
20
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
8
15
0
8
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
0
0
0
0
0
8
0
29
0
% D
% Glu:
0
0
0
22
15
8
0
0
8
0
0
15
50
15
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
36
0
22
0
0
8
8
0
0
% G
% His:
0
0
0
8
0
0
8
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
8
8
8
0
0
0
0
% I
% Lys:
0
8
22
8
15
0
0
15
8
8
8
8
0
0
0
% K
% Leu:
0
8
0
8
0
0
15
8
0
0
0
0
0
15
15
% L
% Met:
0
8
15
0
8
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
43
8
0
29
29
43
8
8
15
36
8
0
0
0
36
% P
% Gln:
0
8
15
8
0
8
8
0
0
0
0
22
8
0
15
% Q
% Arg:
8
0
0
0
0
0
8
0
8
8
36
8
0
0
0
% R
% Ser:
0
43
0
0
0
0
0
0
0
8
0
0
8
8
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
8
8
8
0
8
% T
% Val:
8
0
29
8
0
8
8
0
8
0
8
15
0
15
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
29
0
15
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _