KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
7.58
Human Site:
T1299
Identified Species:
12.82
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
T1299
S
P
P
P
E
P
E
T
T
D
A
S
H
P
S
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
P1132
S
P
P
S
V
P
L
P
P
P
E
P
P
A
G
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
P66
A
R
P
D
S
Q
F
P
P
S
G
A
R
E
V
Dog
Lupus familis
XP_543382
1925
209302
T1301
S
P
P
P
E
P
D
T
P
D
P
A
H
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
T1361
S
P
P
P
E
P
E
T
P
E
P
P
K
P
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
I137
G
E
V
E
E
V
E
I
L
Y
N
P
K
N
K
Chicken
Gallus gallus
Q5F3P8
2008
223067
Q1371
P
P
E
K
F
P
E
Q
L
M
V
T
K
T
S
Frog
Xenopus laevis
Q66J90
1938
216239
H1319
C
L
L
P
P
E
K
H
T
G
H
L
K
V
T
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
E1242
Q
S
L
L
P
P
P
E
T
L
P
D
M
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
F1082
D
C
K
Q
K
P
S
F
E
Y
D
R
I
Y
S
Honey Bee
Apis mellifera
XP_395451
1406
159180
E848
E
S
D
K
E
D
N
E
K
I
D
D
K
S
V
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
S949
F
S
S
T
S
I
Q
S
S
P
E
R
Q
R
D
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
K1229
S
P
P
K
E
E
E
K
V
P
K
K
P
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
R755
S
D
D
G
V
D
N
R
Y
S
M
I
R
D
T
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
26.6
6.6
66.6
N.A.
60
N.A.
N.A.
13.3
26.6
13.3
20
N.A.
13.3
6.6
0
40
P-Site Similarity:
100
26.6
20
80
N.A.
66.6
N.A.
N.A.
13.3
33.3
26.6
20
N.A.
20
6.6
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
8
15
0
8
0
% A
% Cys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
15
8
0
15
8
0
0
15
15
15
0
8
8
% D
% Glu:
8
8
8
8
43
15
36
15
8
8
15
0
0
8
0
% E
% Phe:
8
0
0
0
8
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
0
0
0
0
0
8
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
8
0
15
0
0
% H
% Ile:
0
0
0
0
0
8
0
8
0
8
0
8
8
0
0
% I
% Lys:
0
0
8
22
8
0
8
8
8
0
8
8
36
0
8
% K
% Leu:
0
8
15
8
0
0
8
0
15
8
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
15
0
0
0
8
0
0
8
0
% N
% Pro:
8
43
43
29
15
50
8
15
29
22
22
22
15
36
22
% P
% Gln:
8
0
0
8
0
8
8
8
0
0
0
0
8
0
0
% Q
% Arg:
0
8
0
0
0
0
0
8
0
0
0
15
15
8
0
% R
% Ser:
43
22
8
8
15
0
8
8
8
15
0
8
0
8
22
% S
% Thr:
0
0
0
8
0
0
0
22
22
0
0
8
0
8
15
% T
% Val:
0
0
8
0
15
8
0
0
8
0
8
0
0
8
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
15
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _