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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHF8 All Species: 12.73
Human Site: S967 Identified Species: 25.45
UniProt: Q9UPP1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UPP1 NP_055922.1 1060 117864 S967 A T P Q L V T S S S P L P P P
Chimpanzee Pan troglodytes XP_521077 902 100718 S821 N L Q S S S S S P A T S S L Q
Rhesus Macaque Macaca mulatta XP_001109325 941 106786 Q860 L Q N G K Y M Q N S N L T S G
Dog Lupus familis XP_549017 1024 113801 S931 T T P Q L L T S T S P P P P P
Cat Felis silvestris
Mouse Mus musculus Q80TJ7 1023 113535 S930 T T P Q P D T S S S P Q P P P
Rat Rattus norvegicus NP_001101723 1023 113534 S930 T T P Q P V T S S S P Q P P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508529 1024 113352 P931 S E P S V P V P P S P P P P A
Chicken Gallus gallus XP_414324 1061 118324 P968 S T N N V N K P A Q E G S S P
Frog Xenopus laevis NP_001085579 419 48261 F338 C M A F G G N F L H N L N I G
Zebra Danio Brachydanio rerio XP_694899 1032 114204 E920 V S P P L P S E P P V D C I V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394272 917 104227 T836 Q S S T T K R T Y N K K K Q K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789776 951 107984 E870 K R A A E P L E D I P S T S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.3 39.1 93.7 N.A. 91.5 91.7 N.A. 76.3 50.5 26.4 61.5 N.A. N.A. 35.6 N.A. 36.5
Protein Similarity: 100 80.5 55.4 95.2 N.A. 94.2 94.3 N.A. 83.5 67.1 33.2 72 N.A. N.A. 51.7 N.A. 54.3
P-Site Identity: 100 6.6 13.3 73.3 N.A. 73.3 80 N.A. 33.3 13.3 6.6 13.3 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 20 20 86.6 N.A. 73.3 80 N.A. 46.6 33.3 6.6 26.6 N.A. N.A. 20 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 17 9 0 0 0 0 9 9 0 0 0 0 9 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 0 0 0 9 0 0 9 0 0 9 0 0 0 % D
% Glu: 0 9 0 0 9 0 0 17 0 0 9 0 0 0 0 % E
% Phe: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 9 9 0 0 0 0 0 9 0 0 17 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 0 0 17 0 % I
% Lys: 9 0 0 0 9 9 9 0 0 0 9 9 9 0 9 % K
% Leu: 9 9 0 0 25 9 9 0 9 0 0 25 0 9 0 % L
% Met: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 17 9 0 9 9 0 9 9 17 0 9 0 0 % N
% Pro: 0 0 50 9 17 25 0 17 25 9 50 17 42 42 42 % P
% Gln: 9 9 9 34 0 0 0 9 0 9 0 17 0 9 9 % Q
% Arg: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % R
% Ser: 17 17 9 17 9 9 17 42 25 50 0 17 17 25 9 % S
% Thr: 25 42 0 9 9 0 34 9 9 0 9 0 17 0 0 % T
% Val: 9 0 0 0 17 17 9 0 0 0 9 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _