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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHF8
All Species:
0.91
Human Site:
S177
Identified Species:
1.82
UniProt:
Q9UPP1
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPP1
NP_055922.1
1060
117864
S177
G
M
T
L
P
S
P
S
F
T
V
R
D
V
E
Chimpanzee
Pan troglodytes
XP_521077
902
100718
V88
G
R
A
K
M
A
S
V
P
V
Y
C
L
C
R
Rhesus Macaque
Macaca mulatta
XP_001109325
941
106786
L126
T
R
T
F
I
K
E
L
R
S
R
V
F
P
S
Dog
Lupus familis
XP_549017
1024
113801
V176
K
M
K
L
G
D
F
V
K
Y
Y
Y
S
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80TJ7
1023
113535
V176
K
M
K
L
G
D
F
V
K
Y
Y
Y
S
G
K
Rat
Rattus norvegicus
NP_001101723
1023
113534
V176
K
M
K
L
G
D
F
V
K
Y
Y
Y
S
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508529
1024
113352
G186
F
V
K
Y
Y
C
S
G
K
R
E
K
V
L
N
Chicken
Gallus gallus
XP_414324
1061
118324
S183
E
F
V
D
Y
Y
Y
S
T
N
R
K
R
V
L
Frog
Xenopus laevis
NP_001085579
419
48261
Zebra Danio
Brachydanio rerio
XP_694899
1032
114204
M174
S
R
Q
A
D
L
K
M
K
L
G
E
F
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394272
917
104227
D103
S
R
H
F
P
K
A
D
E
V
V
K
H
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789776
951
107984
V137
K
E
G
L
G
L
I
V
P
P
P
T
F
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.3
39.1
93.7
N.A.
91.5
91.7
N.A.
76.3
50.5
26.4
61.5
N.A.
N.A.
35.6
N.A.
36.5
Protein Similarity:
100
80.5
55.4
95.2
N.A.
94.2
94.3
N.A.
83.5
67.1
33.2
72
N.A.
N.A.
51.7
N.A.
54.3
P-Site Identity:
100
6.6
6.6
13.3
N.A.
13.3
13.3
N.A.
0
13.3
0
13.3
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
100
13.3
13.3
20
N.A.
20
20
N.A.
20
20
0
13.3
N.A.
N.A.
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
9
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
9
0
9
0
% C
% Asp:
0
0
0
9
9
25
0
9
0
0
0
0
9
0
0
% D
% Glu:
9
9
0
0
0
0
9
0
9
0
9
9
0
0
17
% E
% Phe:
9
9
0
17
0
0
25
0
9
0
0
0
25
0
0
% F
% Gly:
17
0
9
0
34
0
0
9
0
0
9
0
0
25
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
34
0
34
9
0
17
9
0
42
0
0
25
0
0
25
% K
% Leu:
0
0
0
42
0
17
0
9
0
9
0
0
9
9
9
% L
% Met:
0
34
0
0
9
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% N
% Pro:
0
0
0
0
17
0
9
0
17
9
9
0
0
9
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
34
0
0
0
0
0
0
9
9
17
9
9
0
17
% R
% Ser:
17
0
0
0
0
9
17
17
0
9
0
0
25
0
9
% S
% Thr:
9
0
17
0
0
0
0
0
9
9
0
9
0
9
0
% T
% Val:
0
9
9
0
0
0
0
42
0
17
17
9
9
34
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
17
9
9
0
0
25
34
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _