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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD1
All Species:
31.21
Human Site:
T392
Identified Species:
57.22
UniProt:
Q9UP38
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UP38
NP_003496.1
647
71158
T392
F
A
E
D
G
A
R
T
V
A
Q
G
T
K
K
Chimpanzee
Pan troglodytes
XP_519190
643
70814
T388
F
A
E
D
G
A
R
T
V
A
Q
G
T
K
K
Rhesus Macaque
Macaca mulatta
XP_001092281
720
78423
T465
F
T
E
D
G
A
R
T
V
A
Q
G
T
K
K
Dog
Lupus familis
XP_539411
651
71536
T396
F
S
E
D
G
A
R
T
V
A
Q
G
T
K
K
Cat
Felis silvestris
Mouse
Mus musculus
O70421
642
70937
T387
F
A
E
D
G
A
R
T
V
A
Q
G
T
N
K
Rat
Rattus norvegicus
Q08463
641
71009
T386
F
A
E
D
G
A
R
T
V
A
Q
G
T
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519817
718
80521
T470
F
S
D
D
G
Y
R
T
V
V
Q
G
T
K
K
Chicken
Gallus gallus
O57328
592
65472
T341
F
A
E
D
G
S
R
T
V
A
Q
G
T
K
R
Frog
Xenopus laevis
Q9I9M5
559
62852
E319
V
A
Q
G
T
K
K
E
G
C
T
F
L
F
M
Zebra Danio
Brachydanio rerio
NP_001124086
538
60387
C301
Q
G
T
K
K
E
G
C
T
I
L
F
M
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
I327
R
L
Q
M
M
S
T
I
T
Q
G
H
R
Q
T
Honey Bee
Apis mellifera
XP_623523
571
64519
T317
I
Q
M
A
S
T
I
T
Q
G
T
K
H
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781961
563
63859
M320
M
L
L
Y
F
F
Q
M
A
S
C
L
W
W
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
86.3
96.4
N.A.
92.7
93
N.A.
65.8
81.9
75.4
70.3
N.A.
43.7
49.6
N.A.
50.7
Protein Similarity:
100
99.3
86.8
97
N.A.
93.8
93.8
N.A.
73.6
85.7
81.3
76.8
N.A.
56.8
61
N.A.
63.3
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
100
N.A.
73.3
86.6
6.6
0
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
100
N.A.
86.6
100
20
0
N.A.
20
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
47
0
8
0
47
0
0
8
54
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
8
8
0
0
0
0
% C
% Asp:
0
0
8
62
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
54
0
0
8
0
8
0
0
0
0
0
8
0
% E
% Phe:
62
0
0
0
8
8
0
0
0
0
0
16
0
8
0
% F
% Gly:
0
8
0
8
62
0
8
0
8
8
8
62
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% H
% Ile:
8
0
0
0
0
0
8
8
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
8
8
8
8
0
0
0
0
8
0
54
54
% K
% Leu:
0
16
8
0
0
0
0
0
0
0
8
8
8
0
16
% L
% Met:
8
0
8
8
8
0
0
8
0
0
0
0
8
8
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
16
0
0
0
8
0
8
8
62
0
0
8
0
% Q
% Arg:
8
0
0
0
0
0
62
0
0
0
0
0
8
0
8
% R
% Ser:
0
16
0
0
8
16
0
0
0
8
0
0
0
0
0
% S
% Thr:
0
8
8
0
8
8
8
70
16
0
16
0
62
0
8
% T
% Val:
8
0
0
0
0
0
0
0
62
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% W
% Tyr:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _