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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD1
All Species:
15.15
Human Site:
S269
Identified Species:
27.78
UniProt:
Q9UP38
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UP38
NP_003496.1
647
71158
S269
F
P
G
G
A
G
A
S
E
R
G
K
F
S
C
Chimpanzee
Pan troglodytes
XP_519190
643
70814
S265
F
P
G
G
A
G
A
S
E
R
G
K
F
S
C
Rhesus Macaque
Macaca mulatta
XP_001092281
720
78423
S342
F
P
G
G
A
S
A
S
E
R
G
K
F
S
C
Dog
Lupus familis
XP_539411
651
71536
S273
F
P
G
G
A
G
A
S
E
R
G
K
F
S
C
Cat
Felis silvestris
Mouse
Mus musculus
O70421
642
70937
V264
Y
P
G
G
A
G
T
V
E
R
G
K
F
S
C
Rat
Rattus norvegicus
Q08463
641
71009
V263
Y
P
G
G
A
G
P
V
E
R
G
K
F
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519817
718
80521
T347
G
G
A
P
R
Y
A
T
L
D
R
P
F
H
C
Chicken
Gallus gallus
O57328
592
65472
E218
A
G
G
S
G
P
G
E
A
R
G
R
F
S
C
Frog
Xenopus laevis
Q9I9M5
559
62852
Y204
R
A
L
K
V
P
A
Y
V
N
Y
H
F
L
G
Zebra Danio
Brachydanio rerio
NP_001124086
538
60387
L186
S
L
R
V
P
P
Y
L
N
Y
R
F
M
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
K210
F
V
C
P
V
Q
L
K
T
P
L
G
M
G
Y
Honey Bee
Apis mellifera
XP_623523
571
64519
P202
C
P
M
Q
F
K
V
P
H
E
L
G
Y
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781961
563
63859
A205
W
D
Y
T
F
M
R
A
Q
N
C
G
A
P
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
86.3
96.4
N.A.
92.7
93
N.A.
65.8
81.9
75.4
70.3
N.A.
43.7
49.6
N.A.
50.7
Protein Similarity:
100
99.3
86.8
97
N.A.
93.8
93.8
N.A.
73.6
85.7
81.3
76.8
N.A.
56.8
61
N.A.
63.3
P-Site Identity:
100
100
93.3
100
N.A.
80
80
N.A.
20
40
13.3
0
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
86.6
86.6
N.A.
26.6
46.6
13.3
0
N.A.
6.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
47
0
47
8
8
0
0
0
8
0
0
% A
% Cys:
8
0
8
0
0
0
0
0
0
0
8
0
0
0
70
% C
% Asp:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
47
8
0
0
0
0
8
% E
% Phe:
39
0
0
0
16
0
0
0
0
0
0
8
70
0
0
% F
% Gly:
8
16
54
47
8
39
8
0
0
0
54
24
0
16
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
8
0
8
0
0
0
47
0
0
0
% K
% Leu:
0
8
8
0
0
0
8
8
8
0
16
0
0
8
8
% L
% Met:
0
0
8
0
0
8
0
0
0
0
0
0
16
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
16
0
0
0
0
0
% N
% Pro:
0
54
0
16
8
24
8
8
0
8
0
8
0
8
0
% P
% Gln:
0
0
0
8
0
8
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
0
8
0
8
0
8
0
0
54
16
8
0
0
0
% R
% Ser:
8
0
0
8
0
8
0
31
0
0
0
0
0
62
0
% S
% Thr:
0
0
0
8
0
0
8
8
8
0
0
0
0
0
0
% T
% Val:
0
8
0
8
16
0
8
16
8
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
8
0
0
8
8
8
0
8
8
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _