KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinector
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTF2
All Species:
32.73
Human Site:
Y777
Identified Species:
60
UniProt:
Q9UNY4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNY4
NP_003585.3
1162
129588
Y777
Q
N
N
L
L
D
M
Y
S
L
L
K
F
L
R
Chimpanzee
Pan troglodytes
XP_513683
1162
129565
Y777
Q
N
N
L
L
D
M
Y
S
L
L
K
F
L
R
Rhesus Macaque
Macaca mulatta
XP_001112999
1163
129401
Y778
Q
N
N
L
L
D
M
Y
S
L
L
K
F
L
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q5NC05
1138
125512
Y753
Q
N
N
L
L
D
M
Y
S
L
M
K
F
L
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416595
1178
129334
Y791
Q
N
N
L
L
D
M
Y
S
L
L
R
F
L
R
Frog
Xenopus laevis
NP_001084942
1187
131668
Y801
Q
N
N
L
L
D
M
Y
S
L
L
R
F
L
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
S681
R
L
N
L
L
M
K
S
L
M
L
R
R
T
K
Honey Bee
Apis mellifera
XP_393754
954
109196
M588
V
T
V
M
K
T
L
M
L
R
R
T
K
Q
E
Nematode Worm
Caenorhab. elegans
NP_502137
1091
122548
Y696
H
N
N
L
W
D
L
Y
S
L
V
R
F
L
R
Sea Urchin
Strong. purpuratus
XP_787293
600
68137
T234
V
K
N
D
E
A
S
T
G
S
K
N
Q
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIY7
1277
144314
Y862
Q
N
K
L
E
D
L
Y
S
L
L
C
F
L
H
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
E424
N
I
Q
K
F
G
V
E
G
P
G
L
E
S
F
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
F769
V
N
R
L
E
D
L
F
S
L
V
R
F
L
R
Conservation
Percent
Protein Identity:
100
99.1
95.8
N.A.
N.A.
70.3
N.A.
N.A.
N.A.
53.5
51
N.A.
N.A.
32.1
31.8
28.3
26.8
Protein Similarity:
100
99.4
96.9
N.A.
N.A.
79.6
N.A.
N.A.
N.A.
66.2
66.8
N.A.
N.A.
51.2
49.3
48.5
37.3
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
93.3
93.3
N.A.
N.A.
26.6
0
66.6
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
53.3
13.3
86.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
21.3
21.3
Protein Similarity:
N.A.
N.A.
N.A.
42.6
37.8
39.9
P-Site Identity:
N.A.
N.A.
N.A.
66.6
0
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
6.6
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
8
0
70
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
24
0
0
8
0
0
0
0
8
0
8
% E
% Phe:
0
0
0
0
8
0
0
8
0
0
0
0
70
0
8
% F
% Gly:
0
0
0
0
0
8
0
0
16
0
8
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
8
8
8
0
8
0
0
0
8
31
8
0
8
% K
% Leu:
0
8
0
77
54
0
31
0
16
70
54
8
0
70
0
% L
% Met:
0
0
0
8
0
8
47
8
0
8
8
0
0
0
0
% M
% Asn:
8
70
70
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% P
% Gln:
54
0
8
0
0
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
8
0
8
0
0
0
0
0
0
8
8
39
8
0
62
% R
% Ser:
0
0
0
0
0
0
8
8
70
8
0
0
0
8
0
% S
% Thr:
0
8
0
0
0
8
0
8
0
0
0
8
0
8
0
% T
% Val:
24
0
8
0
0
0
8
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _