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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTF2
All Species:
12.12
Human Site:
T640
Identified Species:
22.22
UniProt:
Q9UNY4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNY4
NP_003585.3
1162
129588
T640
K
D
D
S
C
D
F
T
S
H
G
T
L
I
I
Chimpanzee
Pan troglodytes
XP_513683
1162
129565
T640
K
D
D
S
C
D
F
T
S
H
G
T
L
I
I
Rhesus Macaque
Macaca mulatta
XP_001112999
1163
129401
T641
K
D
D
S
S
E
L
T
S
H
G
T
L
I
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q5NC05
1138
125512
T616
K
N
D
S
S
V
F
T
S
S
G
T
L
I
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416595
1178
129334
P651
R
N
D
S
T
V
I
P
S
C
S
T
L
I
I
Frog
Xenopus laevis
NP_001084942
1187
131668
V661
K
T
D
S
T
L
V
V
T
R
G
T
L
I
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
V556
R
Q
K
L
T
V
C
V
H
H
G
N
N
R
E
Honey Bee
Apis mellifera
XP_393754
954
109196
H463
M
L
S
V
E
V
Y
H
G
T
N
R
E
N
V
Nematode Worm
Caenorhab. elegans
NP_502137
1091
122548
R567
W
D
A
E
I
D
R
R
L
D
D
S
V
L
S
Sea Urchin
Strong. purpuratus
XP_787293
600
68137
G109
E
A
Q
E
S
P
C
G
G
I
L
A
D
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIY7
1277
144314
M696
M
G
L
G
K
T
V
M
T
I
A
L
I
L
A
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
F298
F
R
K
Q
N
Y
G
F
R
R
K
N
G
L
F
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
G625
P
R
L
P
T
V
S
G
Q
K
T
T
I
D
A
Conservation
Percent
Protein Identity:
100
99.1
95.8
N.A.
N.A.
70.3
N.A.
N.A.
N.A.
53.5
51
N.A.
N.A.
32.1
31.8
28.3
26.8
Protein Similarity:
100
99.4
96.9
N.A.
N.A.
79.6
N.A.
N.A.
N.A.
66.2
66.8
N.A.
N.A.
51.2
49.3
48.5
37.3
P-Site Identity:
100
100
80
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
46.6
46.6
N.A.
N.A.
13.3
0
13.3
0
P-Site Similarity:
100
100
86.6
N.A.
N.A.
80
N.A.
N.A.
N.A.
60
60
N.A.
N.A.
20
13.3
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
21.3
21.3
Protein Similarity:
N.A.
N.A.
N.A.
42.6
37.8
39.9
P-Site Identity:
N.A.
N.A.
N.A.
0
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
0
0
0
8
8
0
0
16
% A
% Cys:
0
0
0
0
16
0
16
0
0
8
0
0
0
0
0
% C
% Asp:
0
31
47
0
0
24
0
0
0
8
8
0
8
8
0
% D
% Glu:
8
0
0
16
8
8
0
0
0
0
0
0
8
8
8
% E
% Phe:
8
0
0
0
0
0
24
8
0
0
0
0
0
0
8
% F
% Gly:
0
8
0
8
0
0
8
16
16
0
47
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
8
31
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
0
16
0
0
16
47
31
% I
% Lys:
39
0
16
0
8
0
0
0
0
8
8
0
0
0
0
% K
% Leu:
0
8
16
8
0
8
8
0
8
0
8
8
47
24
0
% L
% Met:
16
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
16
0
0
8
0
0
0
0
0
8
16
8
8
0
% N
% Pro:
8
0
0
8
0
8
0
8
0
0
0
0
0
0
8
% P
% Gln:
0
8
8
8
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
16
16
0
0
0
0
8
8
8
16
0
8
0
8
0
% R
% Ser:
0
0
8
47
24
0
8
0
39
8
8
8
0
0
8
% S
% Thr:
0
8
0
0
31
8
0
31
16
8
8
54
0
0
0
% T
% Val:
0
0
0
8
0
39
16
16
0
0
0
0
8
0
24
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _