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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTF2
All Species:
11.21
Human Site:
T458
Identified Species:
20.56
UniProt:
Q9UNY4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNY4
NP_003585.3
1162
129588
T458
E
E
V
L
S
G
L
T
L
S
P
E
Q
G
T
Chimpanzee
Pan troglodytes
XP_513683
1162
129565
T458
E
E
V
L
S
G
L
T
L
S
P
E
Q
G
T
Rhesus Macaque
Macaca mulatta
XP_001112999
1163
129401
A459
E
E
A
L
S
G
L
A
L
S
P
E
Q
G
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q5NC05
1138
125512
A434
E
D
A
L
S
A
L
A
L
S
P
E
Q
G
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416595
1178
129334
T459
S
A
L
N
I
S
T
T
D
T
I
E
K
G
E
Frog
Xenopus laevis
NP_001084942
1187
131668
S465
E
D
A
L
S
S
L
S
L
S
P
E
T
S
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
N386
D
E
L
S
E
A
V
N
E
I
K
P
V
Y
T
Honey Bee
Apis mellifera
XP_393754
954
109196
Y298
D
S
S
Y
N
S
D
Y
I
S
S
K
L
K
S
Nematode Worm
Caenorhab. elegans
NP_502137
1091
122548
G394
G
S
V
M
T
Q
N
G
L
L
P
K
R
H
I
Sea Urchin
Strong. purpuratus
XP_787293
600
68137
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIY7
1277
144314
R438
W
K
V
P
N
I
V
R
F
S
T
K
R
C
G
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
K133
K
K
K
K
T
S
T
K
K
K
S
P
K
V
T
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
A433
R
K
D
L
L
E
A
A
D
S
A
E
K
K
A
Conservation
Percent
Protein Identity:
100
99.1
95.8
N.A.
N.A.
70.3
N.A.
N.A.
N.A.
53.5
51
N.A.
N.A.
32.1
31.8
28.3
26.8
Protein Similarity:
100
99.4
96.9
N.A.
N.A.
79.6
N.A.
N.A.
N.A.
66.2
66.8
N.A.
N.A.
51.2
49.3
48.5
37.3
P-Site Identity:
100
100
86.6
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
20
53.3
N.A.
N.A.
13.3
6.6
20
0
P-Site Similarity:
100
100
86.6
N.A.
N.A.
80
N.A.
N.A.
N.A.
40
66.6
N.A.
N.A.
33.3
40
46.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
21.3
21.3
Protein Similarity:
N.A.
N.A.
N.A.
42.6
37.8
39.9
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
24
0
0
16
8
24
0
0
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
16
16
8
0
0
0
8
0
16
0
0
0
0
0
0
% D
% Glu:
39
31
0
0
8
8
0
0
8
0
0
54
0
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
24
0
8
0
0
0
0
0
39
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
8
8
0
0
8
8
8
0
0
0
8
% I
% Lys:
8
24
8
8
0
0
0
8
8
8
8
24
24
16
0
% K
% Leu:
0
0
16
47
8
0
39
0
47
8
0
0
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
16
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
47
16
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
31
0
0
% Q
% Arg:
8
0
0
0
0
0
0
8
0
0
0
0
16
0
0
% R
% Ser:
8
16
8
8
39
31
0
8
0
62
16
0
0
8
8
% S
% Thr:
0
0
0
0
16
0
16
24
0
8
8
0
8
0
47
% T
% Val:
0
0
31
0
0
0
16
0
0
0
0
0
8
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _