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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTF2 All Species: 25.45
Human Site: S994 Identified Species: 46.67
UniProt: Q9UNY4 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNY4 NP_003585.3 1162 129588 S994 M R E S T K I S S L L A E L E
Chimpanzee Pan troglodytes XP_513683 1162 129565 S994 M R E S T K I S S L L A E L E
Rhesus Macaque Macaca mulatta XP_001112999 1163 129401 S995 T R E S T K I S S L L A E L E
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q5NC05 1138 125512 S970 T R R S T K V S S L L A E L E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416595 1178 129334 S1010 S K E S T K V S H L L A E L K
Frog Xenopus laevis NP_001084942 1187 131668 S1018 E S Q S T K I S S L V S E L K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P34739 1061 118357 N893 H R P S S K I N M V I Q I L K
Honey Bee Apis mellifera XP_393754 954 109196 K800 E I L E K N D K L I I V S Q W
Nematode Worm Caenorhab. elegans NP_502137 1091 122548 S916 I F D P D Y L S C K I K N T L
Sea Urchin Strong. purpuratus XP_787293 600 68137 I446 P S F L S T K I K F V I N L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FIY7 1277 144314 S1112 W K E S S K V S E L L K C L E
Baker's Yeast Sacchar. cerevisiae P31244 790 91412 R636 Y K L R S N K R T I K S I V F
Red Bread Mold Neurospora crassa Q7S1P9 1222 137173 V1053 N D S S A K I V A L I S H L R
Conservation
Percent
Protein Identity: 100 99.1 95.8 N.A. N.A. 70.3 N.A. N.A. N.A. 53.5 51 N.A. N.A. 32.1 31.8 28.3 26.8
Protein Similarity: 100 99.4 96.9 N.A. N.A. 79.6 N.A. N.A. N.A. 66.2 66.8 N.A. N.A. 51.2 49.3 48.5 37.3
P-Site Identity: 100 100 93.3 N.A. N.A. 80 N.A. N.A. N.A. 66.6 60 N.A. N.A. 33.3 0 6.6 6.6
P-Site Similarity: 100 100 93.3 N.A. N.A. 86.6 N.A. N.A. N.A. 86.6 86.6 N.A. N.A. 66.6 13.3 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. 23.1 21.3 21.3
Protein Similarity: N.A. N.A. N.A. 42.6 37.8 39.9
P-Site Identity: N.A. N.A. N.A. 53.3 0 33.3
P-Site Similarity: N.A. N.A. N.A. 73.3 40 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 8 0 0 39 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % C
% Asp: 0 8 8 0 8 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 16 0 39 8 0 0 0 0 8 0 0 0 47 0 39 % E
% Phe: 0 8 8 0 0 0 0 0 0 8 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % H
% Ile: 8 8 0 0 0 0 47 8 0 16 31 8 16 0 0 % I
% Lys: 0 24 0 0 8 70 16 8 8 8 8 16 0 0 24 % K
% Leu: 0 0 16 8 0 0 8 0 8 62 47 0 0 77 16 % L
% Met: 16 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 16 0 8 0 0 0 0 16 0 0 % N
% Pro: 8 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 8 0 8 0 % Q
% Arg: 0 39 8 8 0 0 0 8 0 0 0 0 0 0 8 % R
% Ser: 8 16 8 70 31 0 0 62 39 0 0 24 8 0 0 % S
% Thr: 16 0 0 0 47 8 0 0 8 0 0 0 0 8 0 % T
% Val: 0 0 0 0 0 0 24 8 0 8 16 8 0 8 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _