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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTF2
All Species:
13.33
Human Site:
S666
Identified Species:
24.44
UniProt:
Q9UNY4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNY4
NP_003585.3
1162
129588
S666
E
V
E
K
R
V
N
S
N
K
L
R
V
Y
L
Chimpanzee
Pan troglodytes
XP_513683
1162
129565
S666
E
V
E
K
R
V
N
S
N
K
L
R
V
Y
L
Rhesus Macaque
Macaca mulatta
XP_001112999
1163
129401
S667
E
V
E
K
R
V
N
S
N
K
L
R
V
Y
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q5NC05
1138
125512
S642
E
V
E
K
R
V
T
S
N
R
L
R
I
Y
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416595
1178
129334
F677
E
I
D
R
R
V
S
F
G
K
L
R
V
Y
L
Frog
Xenopus laevis
NP_001084942
1187
131668
G687
E
V
E
K
R
V
A
G
S
R
L
K
V
Y
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
V582
V
V
T
T
Y
Q
I
V
A
R
E
H
K
S
L
Honey Bee
Apis mellifera
XP_393754
954
109196
R489
T
T
Y
N
I
L
T
R
E
F
K
T
N
S
T
Nematode Worm
Caenorhab. elegans
NP_502137
1091
122548
A593
D
I
D
A
R
R
L
A
R
Y
D
V
V
I
T
Sea Urchin
Strong. purpuratus
XP_787293
600
68137
R135
V
I
K
A
V
A
A
R
K
A
Q
K
G
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIY7
1277
144314
A722
V
L
V
A
D
V
N
A
D
K
R
N
R
K
E
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
A324
Y
R
V
I
L
D
E
A
H
N
I
K
D
R
Q
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
E651
L
L
A
Q
W
Q
S
E
A
E
N
A
S
K
E
Conservation
Percent
Protein Identity:
100
99.1
95.8
N.A.
N.A.
70.3
N.A.
N.A.
N.A.
53.5
51
N.A.
N.A.
32.1
31.8
28.3
26.8
Protein Similarity:
100
99.4
96.9
N.A.
N.A.
79.6
N.A.
N.A.
N.A.
66.2
66.8
N.A.
N.A.
51.2
49.3
48.5
37.3
P-Site Identity:
100
100
100
N.A.
N.A.
80
N.A.
N.A.
N.A.
60
66.6
N.A.
N.A.
13.3
0
13.3
0
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
86.6
86.6
N.A.
N.A.
20
6.6
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
21.3
21.3
Protein Similarity:
N.A.
N.A.
N.A.
42.6
37.8
39.9
P-Site Identity:
N.A.
N.A.
N.A.
20
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
24
0
8
16
24
16
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
0
8
8
0
0
8
0
8
0
8
0
0
% D
% Glu:
47
0
39
0
0
0
8
8
8
8
8
0
0
0
24
% E
% Phe:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% H
% Ile:
0
24
0
8
8
0
8
0
0
0
8
0
8
8
0
% I
% Lys:
0
0
8
39
0
0
0
0
8
39
8
24
8
16
0
% K
% Leu:
8
16
0
0
8
8
8
0
0
0
47
0
0
0
54
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
31
0
31
8
8
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
16
0
0
0
0
8
0
0
0
8
% Q
% Arg:
0
8
0
8
54
8
0
16
8
24
8
39
8
8
0
% R
% Ser:
0
0
0
0
0
0
16
31
8
0
0
0
8
16
0
% S
% Thr:
8
8
8
8
0
0
16
0
0
0
0
8
0
8
16
% T
% Val:
24
47
16
0
8
54
0
8
0
0
0
8
47
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
8
0
0
0
0
8
0
0
0
47
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _