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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTF2
All Species:
22.42
Human Site:
S549
Identified Species:
41.11
UniProt:
Q9UNY4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNY4
NP_003585.3
1162
129588
S549
A
I
G
Q
L
H
R
S
L
E
S
C
P
G
E
Chimpanzee
Pan troglodytes
XP_513683
1162
129565
S549
A
I
G
Q
L
H
R
S
L
E
S
C
P
G
E
Rhesus Macaque
Macaca mulatta
XP_001112999
1163
129401
S550
A
I
D
Q
L
H
R
S
L
E
S
C
P
G
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q5NC05
1138
125512
S525
A
I
D
E
L
H
R
S
L
K
S
C
P
G
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416595
1178
129334
S562
A
I
N
H
L
H
K
S
L
E
S
C
P
T
E
Frog
Xenopus laevis
NP_001084942
1187
131668
S572
A
I
E
H
L
H
K
S
L
E
S
C
P
S
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
S478
K
T
L
T
M
I
S
S
V
L
A
C
K
N
G
Honey Bee
Apis mellifera
XP_393754
954
109196
L388
V
L
A
D
D
M
G
L
G
K
T
L
T
M
I
Nematode Worm
Caenorhab. elegans
NP_502137
1091
122548
R485
G
L
T
W
M
R
W
R
E
T
Q
P
Q
P
G
Sea Urchin
Strong. purpuratus
XP_787293
600
68137
W34
T
K
P
H
N
G
R
W
K
L
T
T
D
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIY7
1277
144314
K536
L
T
I
K
P
Y
Q
K
A
E
F
T
P
E
E
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
L223
K
T
I
Q
T
I
A
L
L
M
N
D
L
T
K
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
S525
R
T
E
D
R
E
T
S
M
H
P
L
W
E
E
Conservation
Percent
Protein Identity:
100
99.1
95.8
N.A.
N.A.
70.3
N.A.
N.A.
N.A.
53.5
51
N.A.
N.A.
32.1
31.8
28.3
26.8
Protein Similarity:
100
99.4
96.9
N.A.
N.A.
79.6
N.A.
N.A.
N.A.
66.2
66.8
N.A.
N.A.
51.2
49.3
48.5
37.3
P-Site Identity:
100
100
93.3
N.A.
N.A.
80
N.A.
N.A.
N.A.
73.3
66.6
N.A.
N.A.
13.3
0
0
6.6
P-Site Similarity:
100
100
93.3
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
80
73.3
N.A.
N.A.
33.3
20
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
21.3
21.3
Protein Similarity:
N.A.
N.A.
N.A.
42.6
37.8
39.9
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
8
0
0
0
8
0
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
54
0
0
0
% C
% Asp:
0
0
16
16
8
0
0
0
0
0
0
8
8
0
0
% D
% Glu:
0
0
16
8
0
8
0
0
8
47
0
0
0
16
54
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
0
16
0
0
8
8
0
8
0
0
0
0
31
16
% G
% His:
0
0
0
24
0
47
0
0
0
8
0
0
0
0
8
% H
% Ile:
0
47
16
0
0
16
0
0
0
0
0
0
0
0
8
% I
% Lys:
16
8
0
8
0
0
16
8
8
16
0
0
8
8
8
% K
% Leu:
8
16
8
0
47
0
0
16
54
16
0
16
8
0
0
% L
% Met:
0
0
0
0
16
8
0
0
8
8
0
0
0
8
0
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
8
0
0
8
0
% N
% Pro:
0
0
8
0
8
0
0
0
0
0
8
8
54
8
8
% P
% Gln:
0
0
0
31
0
0
8
0
0
0
8
0
8
0
0
% Q
% Arg:
8
0
0
0
8
8
39
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
62
0
0
47
0
0
8
0
% S
% Thr:
8
31
8
8
8
0
8
0
0
8
16
16
8
16
0
% T
% Val:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
8
8
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _