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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTF2
All Species:
14.55
Human Site:
S374
Identified Species:
26.67
UniProt:
Q9UNY4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNY4
NP_003585.3
1162
129588
S374
G
S
P
L
L
F
D
S
T
L
D
L
E
T
K
Chimpanzee
Pan troglodytes
XP_513683
1162
129565
S374
G
S
P
L
L
F
D
S
T
L
D
L
E
T
K
Rhesus Macaque
Macaca mulatta
XP_001112999
1163
129401
S375
G
S
P
L
L
F
D
S
T
L
D
L
Q
T
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q5NC05
1138
125512
S350
G
S
P
L
L
F
D
S
T
V
D
S
Q
K
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416595
1178
129334
E371
G
E
P
K
K
S
V
E
G
L
L
P
R
V
V
Frog
Xenopus laevis
NP_001084942
1187
131668
S381
D
D
V
V
F
V
S
S
L
P
A
N
E
K
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
K311
V
Q
V
S
D
A
E
K
L
F
E
K
V
A
H
Honey Bee
Apis mellifera
XP_393754
954
109196
E224
K
M
E
H
L
Q
K
E
L
N
K
T
K
L
L
Nematode Worm
Caenorhab. elegans
NP_502137
1091
122548
V318
L
L
A
K
K
N
K
V
M
G
L
I
S
L
S
Sea Urchin
Strong. purpuratus
XP_787293
600
68137
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIY7
1277
144314
A352
V
E
E
I
K
V
E
A
V
K
M
S
S
Q
V
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
T59
E
E
Y
R
D
D
A
T
L
V
K
S
P
D
D
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
E354
P
E
R
L
R
T
N
E
T
V
F
L
Q
L
K
Conservation
Percent
Protein Identity:
100
99.1
95.8
N.A.
N.A.
70.3
N.A.
N.A.
N.A.
53.5
51
N.A.
N.A.
32.1
31.8
28.3
26.8
Protein Similarity:
100
99.4
96.9
N.A.
N.A.
79.6
N.A.
N.A.
N.A.
66.2
66.8
N.A.
N.A.
51.2
49.3
48.5
37.3
P-Site Identity:
100
100
93.3
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
20
13.3
N.A.
N.A.
0
6.6
0
0
P-Site Similarity:
100
100
100
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
20
20
N.A.
N.A.
13.3
13.3
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
21.3
21.3
Protein Similarity:
N.A.
N.A.
N.A.
42.6
37.8
39.9
P-Site Identity:
N.A.
N.A.
N.A.
0
0
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
8
8
0
0
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
16
8
31
0
0
0
31
0
0
8
8
% D
% Glu:
8
31
16
0
0
0
16
24
0
0
8
0
24
0
0
% E
% Phe:
0
0
0
0
8
31
0
0
0
8
8
0
0
0
0
% F
% Gly:
39
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
8
0
0
16
24
0
16
8
0
8
16
8
8
16
39
% K
% Leu:
8
8
0
39
39
0
0
0
31
31
16
31
0
24
8
% L
% Met:
0
8
0
0
0
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
8
0
8
0
0
0
% N
% Pro:
8
0
39
0
0
0
0
0
0
8
0
8
8
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
0
0
24
8
0
% Q
% Arg:
0
0
8
8
8
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
31
0
8
0
8
8
39
0
0
0
24
16
0
8
% S
% Thr:
0
0
0
0
0
8
0
8
39
0
0
8
0
24
0
% T
% Val:
16
0
16
8
0
16
8
8
8
24
0
0
8
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _