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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTF2 All Species: 12.12
Human Site: S307 Identified Species: 22.22
UniProt: Q9UNY4 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNY4 NP_003585.3 1162 129588 S307 S I Q A T Q K S L P Q G H F Q
Chimpanzee Pan troglodytes XP_513683 1162 129565 S307 S I Q A T Q K S L P Q G H F Q
Rhesus Macaque Macaca mulatta XP_001112999 1163 129401 S308 S T Q A T Q K S L P R G H F Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q5NC05 1138 125512 N281 V S R E P L K N G E A P S A Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416595 1178 129334 P303 N G E M K P I P K E N T T S T
Frog Xenopus laevis NP_001084942 1187 131668 S292 D T R K S S A S V S R G P L L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P34739 1061 118357 A247 S P R S S A G A S V V K T S K
Honey Bee Apis mellifera XP_393754 954 109196 K161 N N N S L T T K Y V S K E K K
Nematode Worm Caenorhab. elegans NP_502137 1091 122548 K253 I I E V T P E K V V S N E K R
Sea Urchin Strong. purpuratus XP_787293 600 68137
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FIY7 1277 144314 D286 L F S S G D S D G T S A K R R
Baker's Yeast Sacchar. cerevisiae P31244 790 91412
Red Bread Mold Neurospora crassa Q7S1P9 1222 137173 T284 T V A R K G Q T K P G T P Q S
Conservation
Percent
Protein Identity: 100 99.1 95.8 N.A. N.A. 70.3 N.A. N.A. N.A. 53.5 51 N.A. N.A. 32.1 31.8 28.3 26.8
Protein Similarity: 100 99.4 96.9 N.A. N.A. 79.6 N.A. N.A. N.A. 66.2 66.8 N.A. N.A. 51.2 49.3 48.5 37.3
P-Site Identity: 100 100 86.6 N.A. N.A. 13.3 N.A. N.A. N.A. 0 13.3 N.A. N.A. 6.6 0 13.3 0
P-Site Similarity: 100 100 93.3 N.A. N.A. 26.6 N.A. N.A. N.A. 13.3 40 N.A. N.A. 40 20 40 0
Percent
Protein Identity: N.A. N.A. N.A. 23.1 21.3 21.3
Protein Similarity: N.A. N.A. N.A. 42.6 37.8 39.9
P-Site Identity: N.A. N.A. N.A. 0 0 6.6
P-Site Similarity: N.A. N.A. N.A. 13.3 0 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 24 0 8 8 8 0 0 8 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 0 16 8 0 0 8 0 0 16 0 0 16 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 24 0 % F
% Gly: 0 8 0 0 8 8 8 0 16 0 8 31 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 24 0 0 % H
% Ile: 8 24 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 8 16 0 31 16 16 0 0 16 8 16 16 % K
% Leu: 8 0 0 0 8 8 0 0 24 0 0 0 0 8 8 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 16 8 8 0 0 0 0 8 0 0 8 8 0 0 0 % N
% Pro: 0 8 0 0 8 16 0 8 0 31 0 8 16 0 0 % P
% Gln: 0 0 24 0 0 24 8 0 0 0 16 0 0 8 31 % Q
% Arg: 0 0 24 8 0 0 0 0 0 0 16 0 0 8 16 % R
% Ser: 31 8 8 24 16 8 8 31 8 8 24 0 8 16 8 % S
% Thr: 8 16 0 0 31 8 8 8 0 8 0 16 16 0 8 % T
% Val: 8 8 0 8 0 0 0 0 16 24 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _