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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTF2
All Species:
10
Human Site:
S221
Identified Species:
18.33
UniProt:
Q9UNY4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNY4
NP_003585.3
1162
129588
S221
R
D
F
S
E
I
K
S
Q
Q
C
Q
G
N
E
Chimpanzee
Pan troglodytes
XP_513683
1162
129565
S221
R
D
F
S
E
I
K
S
Q
Q
C
Q
G
N
E
Rhesus Macaque
Macaca mulatta
XP_001112999
1163
129401
S222
R
D
F
S
E
V
K
S
Q
Q
C
Q
G
K
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q5NC05
1138
125512
R195
T
R
Q
S
G
G
D
R
E
E
Q
E
K
S
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416595
1178
129334
T217
S
K
L
C
L
S
E
T
W
K
G
K
N
T
H
Frog
Xenopus laevis
NP_001084942
1187
131668
K206
K
L
S
A
D
T
S
K
P
S
G
E
E
E
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
A161
G
P
T
E
A
P
T
A
E
A
V
V
P
R
Y
Honey Bee
Apis mellifera
XP_393754
954
109196
K75
L
T
E
E
T
I
K
K
R
I
K
K
H
I
F
Nematode Worm
Caenorhab. elegans
NP_502137
1091
122548
W167
R
A
A
S
G
G
G
W
G
S
S
A
D
V
K
Sea Urchin
Strong. purpuratus
XP_787293
600
68137
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIY7
1277
144314
V200
C
V
D
N
L
V
V
V
K
E
E
E
M
I
A
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
L198
R
V
N
S
H
S
P
L
V
V
G
G
Q
S
P
Conservation
Percent
Protein Identity:
100
99.1
95.8
N.A.
N.A.
70.3
N.A.
N.A.
N.A.
53.5
51
N.A.
N.A.
32.1
31.8
28.3
26.8
Protein Similarity:
100
99.4
96.9
N.A.
N.A.
79.6
N.A.
N.A.
N.A.
66.2
66.8
N.A.
N.A.
51.2
49.3
48.5
37.3
P-Site Identity:
100
100
86.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
0
0
N.A.
N.A.
0
13.3
13.3
0
P-Site Similarity:
100
100
93.3
N.A.
N.A.
40
N.A.
N.A.
N.A.
26.6
26.6
N.A.
N.A.
13.3
26.6
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
21.3
21.3
Protein Similarity:
N.A.
N.A.
N.A.
42.6
37.8
39.9
P-Site Identity:
N.A.
N.A.
N.A.
0
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
0
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
8
0
0
8
0
8
0
8
0
0
8
% A
% Cys:
8
0
0
8
0
0
0
0
0
0
24
0
0
0
0
% C
% Asp:
0
24
8
0
8
0
8
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
8
16
24
0
8
0
16
16
8
24
8
8
24
% E
% Phe:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
16
16
8
0
8
0
24
8
24
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
0
0
24
0
0
0
8
0
0
0
16
0
% I
% Lys:
8
8
0
0
0
0
31
16
8
8
8
16
8
8
16
% K
% Leu:
8
8
8
0
16
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
0
0
0
8
16
0
% N
% Pro:
0
8
0
0
0
8
8
0
8
0
0
0
8
0
8
% P
% Gln:
0
0
8
0
0
0
0
0
24
24
8
24
8
0
0
% Q
% Arg:
39
8
0
0
0
0
0
8
8
0
0
0
0
8
0
% R
% Ser:
8
0
8
47
0
16
8
24
0
16
8
0
0
16
8
% S
% Thr:
8
8
8
0
8
8
8
8
0
0
0
0
0
8
0
% T
% Val:
0
16
0
0
0
16
8
8
8
8
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _