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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR3 All Species: 21.82
Human Site: Y481 Identified Species: 34.29
UniProt: Q9UNX4 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNX4 NP_006775.1 943 106099 Y481 K T G K L Q L Y D L A S G N L
Chimpanzee Pan troglodytes XP_524820 715 79849 G281 A G S I M R E G R D R V V N L
Rhesus Macaque Macaca mulatta XP_001113341 943 106178 Y481 K T G K L Q L Y D L A S G N L
Dog Lupus familis XP_540261 943 106340 Y481 K T G K L Q L Y D L A S G N L
Cat Felis silvestris
Mouse Mus musculus Q8BHB4 942 105757 Y480 K T G N L Q L Y D L A S G T L
Rat Rattus norvegicus NP_001101175 942 106054 Y480 K T G N M Q L Y D L A S G N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511524 938 103974 Y476 K K G K L Q L Y D L A S A S L
Chicken Gallus gallus Q5ZIU8 657 72720 V223 W D L E K F H V V S C I E E E
Frog Xenopus laevis NP_001085274 942 105947 F478 K S G N L Q L F D L A S G N L
Zebra Danio Brachydanio rerio Q7ZUV2 694 75977 E260 T L R V Y G W E P D R C F D V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650705 922 103132 V469 K S G K L L I V D V A A A D I
Honey Bee Apis mellifera XP_624815 920 103453 I465 G K M L I I D I A S G D I L E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188240 693 77355 L259 E V S V V T L L H N N S L E V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_188791 955 106047 I472 K S G V L E I I D I G S A T K
Baker's Yeast Sacchar. cerevisiae Q12220 943 106324 S463 L F D L A S S S L L D T I E D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 98.4 93.4 N.A. 90.9 90.4 N.A. 76.9 20.6 73.2 20.3 N.A. 42.8 47.9 N.A. 42.1
Protein Similarity: 100 72.3 99.3 96.8 N.A. 95.8 95.9 N.A. 88.5 35.7 85.9 34.8 N.A. 65.3 67.1 N.A. 56.7
P-Site Identity: 100 13.3 100 100 N.A. 86.6 86.6 N.A. 80 0 80 0 N.A. 40 0 N.A. 13.3
P-Site Similarity: 100 26.6 100 100 N.A. 86.6 93.3 N.A. 86.6 6.6 93.3 13.3 N.A. 80 6.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 39.6 40.3 N.A.
Protein Similarity: N.A. N.A. N.A. 60.8 61 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 7 0 0 0 7 0 54 7 20 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 7 7 0 0 0 % C
% Asp: 0 7 7 0 0 0 7 0 60 14 7 7 0 14 7 % D
% Glu: 7 0 0 7 0 7 7 7 0 0 0 0 7 20 14 % E
% Phe: 0 7 0 0 0 7 0 7 0 0 0 0 7 0 0 % F
% Gly: 7 7 60 0 0 7 0 7 0 0 14 0 40 0 0 % G
% His: 0 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 7 7 14 14 0 7 0 7 14 0 7 % I
% Lys: 60 14 0 34 7 0 0 0 0 0 0 0 0 0 7 % K
% Leu: 7 7 7 14 54 7 54 7 7 54 0 0 7 7 54 % L
% Met: 0 0 7 0 14 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 20 0 0 0 0 0 7 7 0 0 40 0 % N
% Pro: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 47 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 0 0 7 0 0 7 0 14 0 0 0 0 % R
% Ser: 0 20 14 0 0 7 7 7 0 14 0 60 0 7 0 % S
% Thr: 7 34 0 0 0 7 0 0 0 0 0 7 0 14 0 % T
% Val: 0 7 0 20 7 0 0 14 7 7 0 7 7 0 14 % V
% Trp: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 40 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _