KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR3
All Species:
19.39
Human Site:
Y222
Identified Species:
30.48
UniProt:
Q9UNX4
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNX4
NP_006775.1
943
106099
Y222
L
R
V
W
D
I
A
Y
L
Q
E
I
E
D
P
Chimpanzee
Pan troglodytes
XP_524820
715
79849
N39
P
L
C
S
S
P
L
N
S
E
N
H
N
E
I
Rhesus Macaque
Macaca mulatta
XP_001113341
943
106178
Y222
L
R
V
W
D
I
A
Y
L
Q
E
I
E
D
L
Dog
Lupus familis
XP_540261
943
106340
Y222
L
R
A
W
D
I
T
Y
L
Q
E
V
E
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHB4
942
105757
Y222
L
R
A
W
D
I
D
Y
L
Q
E
I
D
D
P
Rat
Rattus norvegicus
NP_001101175
942
106054
Y222
L
R
A
W
D
I
A
Y
L
Q
E
I
D
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511524
938
103974
W222
L
R
A
W
D
I
T
W
A
Q
P
L
Q
D
P
Chicken
Gallus gallus
Q5ZIU8
657
72720
Frog
Xenopus laevis
NP_001085274
942
105947
Y222
L
R
A
W
N
I
C
Y
I
K
E
G
E
N
T
Zebra Danio
Brachydanio rerio
Q7ZUV2
694
75977
A18
W
K
L
Q
E
I
V
A
H
S
S
N
V
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650705
922
103132
M210
L
A
F
I
G
N
L
M
V
A
G
A
G
E
S
Honey Bee
Apis mellifera
XP_624815
920
103453
F222
L
R
I
W
K
I
S
F
I
E
N
D
N
T
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188240
693
77355
R17
V
N
E
S
G
L
Y
R
L
K
G
H
R
G
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_188791
955
106047
E221
L
R
F
Y
A
V
K
E
Y
S
S
N
G
S
L
Baker's Yeast
Sacchar. cerevisiae
Q12220
943
106324
D214
C
W
G
L
A
V
K
D
D
L
L
I
T
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
98.4
93.4
N.A.
90.9
90.4
N.A.
76.9
20.6
73.2
20.3
N.A.
42.8
47.9
N.A.
42.1
Protein Similarity:
100
72.3
99.3
96.8
N.A.
95.8
95.9
N.A.
88.5
35.7
85.9
34.8
N.A.
65.3
67.1
N.A.
56.7
P-Site Identity:
100
0
93.3
73.3
N.A.
80
86.6
N.A.
53.3
0
46.6
6.6
N.A.
6.6
26.6
N.A.
6.6
P-Site Similarity:
100
13.3
93.3
80
N.A.
86.6
93.3
N.A.
73.3
0
73.3
26.6
N.A.
20
60
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.6
40.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.8
61
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
34
0
14
0
20
7
7
7
0
7
0
0
0
% A
% Cys:
7
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
40
0
7
7
7
0
0
7
14
40
0
% D
% Glu:
0
0
7
0
7
0
0
7
0
14
40
0
27
14
7
% E
% Phe:
0
0
14
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
14
0
0
0
0
0
14
7
14
7
7
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
14
0
0
0
% H
% Ile:
0
0
7
7
0
60
0
0
14
0
0
34
0
0
7
% I
% Lys:
0
7
0
0
7
0
14
0
0
14
0
0
0
0
0
% K
% Leu:
67
7
7
7
0
7
14
0
40
7
7
7
0
0
20
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% M
% Asn:
0
7
0
0
7
7
0
7
0
0
14
14
14
7
0
% N
% Pro:
7
0
0
0
0
7
0
0
0
0
7
0
0
0
27
% P
% Gln:
0
0
0
7
0
0
0
0
0
40
0
0
7
0
0
% Q
% Arg:
0
60
0
0
0
0
0
7
0
0
0
0
7
0
0
% R
% Ser:
0
0
0
14
7
0
7
0
7
14
14
0
0
14
14
% S
% Thr:
0
0
0
0
0
0
14
0
0
0
0
0
7
14
7
% T
% Val:
7
0
14
0
0
14
7
0
7
0
0
7
7
0
0
% V
% Trp:
7
7
0
54
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
7
40
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _