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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR3 All Species: 23.33
Human Site: S823 Identified Species: 36.67
UniProt: Q9UNX4 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNX4 NP_006775.1 943 106099 S823 K S S E L E E S L L V L P F S
Chimpanzee Pan troglodytes XP_524820 715 79849 F606 V K I W G L D F G D C H K S L
Rhesus Macaque Macaca mulatta XP_001113341 943 106178 S823 R S S E L E E S L L V L P F S
Dog Lupus familis XP_540261 943 106340 S823 K S S E L E E S L L V L P F S
Cat Felis silvestris
Mouse Mus musculus Q8BHB4 942 105757 A822 R S S E L E E A L L V L P F S
Rat Rattus norvegicus NP_001101175 942 106054 A822 R S S E L E E A L L V L P F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511524 938 103974 S818 K S S E L E E S L L V L P F S
Chicken Gallus gallus Q5ZIU8 657 72720 Q548 D L L N I V N Q T A S L W K L
Frog Xenopus laevis NP_001085274 942 105947 S822 K S S E L E E S L L V L P F S
Zebra Danio Brachydanio rerio Q7ZUV2 694 75977 K585 V L N I I N L K P S L W K L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650705 922 103132 S806 A L L L L P F S T V C E V L E
Honey Bee Apis mellifera XP_624815 920 103453 L798 A S D L E E S L L L L P Y S A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188240 693 77355 I584 W E K T E E P I V L E E E Q E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_188791 955 106047 T814 R T N D L E Q T L L A L P F S
Baker's Yeast Sacchar. cerevisiae Q12220 943 106324 A820 R M S Q L E D A L M V M P F S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 98.4 93.4 N.A. 90.9 90.4 N.A. 76.9 20.6 73.2 20.3 N.A. 42.8 47.9 N.A. 42.1
Protein Similarity: 100 72.3 99.3 96.8 N.A. 95.8 95.9 N.A. 88.5 35.7 85.9 34.8 N.A. 65.3 67.1 N.A. 56.7
P-Site Identity: 100 0 93.3 100 N.A. 86.6 86.6 N.A. 100 6.6 100 0 N.A. 13.3 26.6 N.A. 13.3
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 100 13.3 100 20 N.A. 20 40 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 39.6 40.3 N.A.
Protein Similarity: N.A. N.A. N.A. 60.8 61 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 93.3 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 0 0 0 0 20 0 7 7 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 % C
% Asp: 7 0 7 7 0 0 14 0 0 7 0 0 0 0 7 % D
% Glu: 0 7 0 47 14 74 47 0 0 0 7 14 7 0 14 % E
% Phe: 0 0 0 0 0 0 7 7 0 0 0 0 0 60 0 % F
% Gly: 0 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 7 7 14 0 0 7 0 0 0 0 0 0 0 % I
% Lys: 27 7 7 0 0 0 0 7 0 0 0 0 14 7 0 % K
% Leu: 0 20 14 14 67 7 7 7 67 67 14 60 0 14 14 % L
% Met: 0 7 0 0 0 0 0 0 0 7 0 7 0 0 0 % M
% Asn: 0 0 14 7 0 7 7 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 7 7 0 7 0 0 7 60 0 0 % P
% Gln: 0 0 0 7 0 0 7 7 0 0 0 0 0 7 0 % Q
% Arg: 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 54 54 0 0 0 7 40 0 7 7 0 0 14 60 % S
% Thr: 0 7 0 7 0 0 0 7 14 0 0 0 0 0 0 % T
% Val: 14 0 0 0 0 7 0 0 7 7 54 0 7 0 0 % V
% Trp: 7 0 0 7 0 0 0 0 0 0 0 7 7 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _