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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR3
All Species:
17.58
Human Site:
S533
Identified Species:
27.62
UniProt:
Q9UNX4
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNX4
NP_006775.1
943
106099
S533
E
L
V
K
D
E
N
S
T
Q
K
R
L
S
V
Chimpanzee
Pan troglodytes
XP_524820
715
79849
K333
K
K
A
R
K
K
A
K
L
H
S
C
K
G
E
Rhesus Macaque
Macaca mulatta
XP_001113341
943
106178
S533
E
L
V
K
D
E
N
S
T
Q
K
R
L
S
V
Dog
Lupus familis
XP_540261
943
106340
S533
E
L
V
K
D
E
N
S
T
Q
K
R
L
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHB4
942
105757
S532
E
L
V
T
D
K
N
S
T
Q
K
R
L
S
V
Rat
Rattus norvegicus
NP_001101175
942
106054
S532
E
L
V
T
D
K
N
S
T
Q
K
R
L
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511524
938
103974
G528
H
L
V
K
D
A
D
G
P
Q
K
R
L
S
V
Chicken
Gallus gallus
Q5ZIU8
657
72720
V275
V
V
V
N
W
G
K
V
A
D
L
S
V
C
H
Frog
Xenopus laevis
NP_001085274
942
105947
E530
E
L
V
N
E
E
T
E
T
Q
S
S
R
R
L
Zebra Danio
Brachydanio rerio
Q7ZUV2
694
75977
I312
V
K
K
S
G
S
V
I
Q
G
L
I
Q
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650705
922
103132
G521
E
L
I
D
A
G
E
G
A
A
Q
T
K
V
L
Honey Bee
Apis mellifera
XP_624815
920
103453
I517
I
Q
D
P
D
R
E
I
K
A
K
I
L
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188240
693
77355
N311
A
V
L
S
A
G
G
N
A
V
K
I
W
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_188791
955
106047
K524
Q
V
K
Q
K
S
G
K
A
T
K
K
L
T
V
Baker's Yeast
Sacchar. cerevisiae
Q12220
943
106324
K515
L
V
P
G
T
K
N
K
F
L
P
V
L
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
98.4
93.4
N.A.
90.9
90.4
N.A.
76.9
20.6
73.2
20.3
N.A.
42.8
47.9
N.A.
42.1
Protein Similarity:
100
72.3
99.3
96.8
N.A.
95.8
95.9
N.A.
88.5
35.7
85.9
34.8
N.A.
65.3
67.1
N.A.
56.7
P-Site Identity:
100
0
100
100
N.A.
86.6
86.6
N.A.
66.6
6.6
40
0
N.A.
13.3
33.3
N.A.
6.6
P-Site Similarity:
100
20
100
100
N.A.
93.3
93.3
N.A.
73.3
20
53.3
0
N.A.
33.3
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.6
40.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.8
61
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
14
7
7
0
27
14
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% C
% Asp:
0
0
7
7
47
0
7
0
0
7
0
0
0
7
0
% D
% Glu:
47
0
0
0
7
27
14
7
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
7
20
14
14
0
7
0
0
0
7
0
% G
% His:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% H
% Ile:
7
0
7
0
0
0
0
14
0
0
0
20
0
0
0
% I
% Lys:
7
14
14
27
14
27
7
20
7
0
60
7
14
7
7
% K
% Leu:
7
54
7
0
0
0
0
0
7
7
14
0
60
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
14
0
0
40
7
0
0
0
0
0
7
0
% N
% Pro:
0
0
7
7
0
0
0
0
7
0
7
0
0
0
0
% P
% Gln:
7
7
0
7
0
0
0
0
7
47
7
0
7
0
0
% Q
% Arg:
0
0
0
7
0
7
0
0
0
0
0
40
7
7
7
% R
% Ser:
0
0
0
14
0
14
0
34
0
0
14
14
0
47
0
% S
% Thr:
0
0
0
14
7
0
7
0
40
7
0
7
0
7
0
% T
% Val:
14
27
54
0
0
0
7
7
0
7
0
7
7
7
54
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _