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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR3
All Species:
9.7
Human Site:
S241
Identified Species:
15.24
UniProt:
Q9UNX4
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNX4
NP_006775.1
943
106099
S241
P
K
K
I
K
G
S
S
P
G
I
Q
D
T
L
Chimpanzee
Pan troglodytes
XP_524820
715
79849
L55
A
Y
F
L
D
V
Y
L
L
E
Y
L
Q
I
L
Rhesus Macaque
Macaca mulatta
XP_001113341
943
106178
S241
P
K
K
I
K
G
S
S
P
G
V
Q
D
T
L
Dog
Lupus familis
XP_540261
943
106340
S241
P
K
K
S
K
G
S
S
P
E
I
Q
D
T
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHB4
942
105757
P241
P
K
K
I
K
E
C
P
G
I
Q
D
T
P
E
Rat
Rattus norvegicus
NP_001101175
942
106054
P241
P
K
K
I
K
E
C
P
G
I
Q
D
T
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511524
938
103974
R238
E
P
D
A
K
R
A
R
G
P
P
P
A
T
P
Chicken
Gallus gallus
Q5ZIU8
657
72720
Frog
Xenopus laevis
NP_001085274
942
105947
S238
E
G
P
Q
S
K
K
S
K
G
P
L
G
E
E
Zebra Danio
Brachydanio rerio
Q7ZUV2
694
75977
R34
V
L
G
K
S
S
G
R
L
L
A
T
G
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650705
922
103132
D228
V
Y
R
L
R
K
H
D
G
A
I
T
E
T
L
Honey Bee
Apis mellifera
XP_624815
920
103453
T238
D
V
N
L
H
N
L
T
L
T
D
D
T
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188240
693
77355
Q33
T
R
V
S
F
M
A
Q
H
N
I
V
I
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_188791
955
106047
E241
A
N
E
I
K
A
S
E
E
H
S
T
E
N
K
Baker's Yeast
Sacchar. cerevisiae
Q12220
943
106324
K230
D
S
Q
V
K
I
W
K
L
D
I
E
N
D
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
98.4
93.4
N.A.
90.9
90.4
N.A.
76.9
20.6
73.2
20.3
N.A.
42.8
47.9
N.A.
42.1
Protein Similarity:
100
72.3
99.3
96.8
N.A.
95.8
95.9
N.A.
88.5
35.7
85.9
34.8
N.A.
65.3
67.1
N.A.
56.7
P-Site Identity:
100
6.6
93.3
80
N.A.
33.3
33.3
N.A.
13.3
0
13.3
0
N.A.
20
0
N.A.
6.6
P-Site Similarity:
100
13.3
100
80
N.A.
33.3
33.3
N.A.
20
0
13.3
0
N.A.
46.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.6
40.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.8
61
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
7
0
7
14
0
0
7
7
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
7
0
7
0
0
7
0
7
7
20
20
7
0
% D
% Glu:
14
0
7
0
0
14
0
7
7
14
0
7
14
14
27
% E
% Phe:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
0
20
7
0
27
20
0
0
14
7
0
% G
% His:
0
0
0
0
7
0
7
0
7
7
0
0
0
0
7
% H
% Ile:
0
0
0
34
0
7
0
0
0
14
34
0
7
7
0
% I
% Lys:
0
34
34
7
54
14
7
7
7
0
0
0
0
0
14
% K
% Leu:
0
7
0
20
0
0
7
7
27
7
0
14
0
0
27
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
0
7
0
0
0
7
0
0
7
7
0
% N
% Pro:
34
7
7
0
0
0
0
14
20
7
14
7
0
14
7
% P
% Gln:
0
0
7
7
0
0
0
7
0
0
14
20
7
0
0
% Q
% Arg:
0
7
7
0
7
7
0
14
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
14
14
7
27
27
0
0
7
0
0
7
7
% S
% Thr:
7
0
0
0
0
0
0
7
0
7
0
20
20
34
0
% T
% Val:
14
7
7
7
0
7
0
0
0
0
7
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
14
0
0
0
0
7
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _