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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIMELESS
All Species:
33.33
Human Site:
T424
Identified Species:
73.33
UniProt:
Q9UNS1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNS1
NP_003911.2
1208
138630
T424
N
Y
Y
E
M
M
L
T
D
R
K
E
A
A
S
Chimpanzee
Pan troglodytes
XP_509535
1209
138911
T424
N
Y
Y
E
M
M
L
T
D
R
K
E
A
A
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538233
1446
163698
T653
N
Y
Y
E
M
M
L
T
D
R
K
E
A
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1X4
1197
137484
T424
N
Y
Y
E
M
M
L
T
D
R
K
E
A
A
S
Rat
Rattus norvegicus
Q9Z2Y1
1205
138547
T424
N
Y
Y
E
M
M
L
T
D
R
K
E
A
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512607
1213
138721
T419
N
Y
Y
E
M
M
L
T
D
R
K
E
A
V
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922924
1278
147885
T424
N
Y
Y
E
M
M
L
T
D
K
S
D
A
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524341
1384
159345
S421
H
D
M
D
M
I
V
S
D
K
K
Q
A
R
L
Honey Bee
Apis mellifera
XP_623203
520
60789
Nematode Worm
Caenorhab. elegans
NP_499594
1353
156992
K422
V
E
N
A
T
T
L
K
G
V
E
A
K
S
H
Sea Urchin
Strong. purpuratus
XP_784350
1529
176104
T429
K
Y
L
D
M
M
T
T
D
K
K
E
A
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.6
N.A.
83.8
81.4
N.A.
70.2
N.A.
N.A.
59.5
N.A.
33.1
20.3
23.2
38
Protein Similarity:
100
99.7
N.A.
77.9
N.A.
90.5
89.6
N.A.
80.4
N.A.
N.A.
73.6
N.A.
53
30.7
43
55.7
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
73.3
N.A.
26.6
0
6.6
60
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
86.6
N.A.
73.3
0
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
10
82
55
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
19
0
0
0
0
82
0
0
10
0
0
0
% D
% Glu:
0
10
0
64
0
0
0
0
0
0
10
64
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
10
0
28
73
0
10
0
0
% K
% Leu:
0
0
10
0
0
0
73
0
0
0
0
0
0
0
10
% L
% Met:
0
0
10
0
82
73
0
0
0
0
0
0
0
0
0
% M
% Asn:
64
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
55
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
10
0
0
10
0
0
10
64
% S
% Thr:
0
0
0
0
10
10
10
73
0
0
0
0
0
10
0
% T
% Val:
10
0
0
0
0
0
10
0
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
73
64
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _