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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TIMELESS All Species: 9.09
Human Site: S982 Identified Species: 20
UniProt: Q9UNS1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNS1 NP_003911.2 1208 138630 S982 E N L P E E D S E E E E E G G
Chimpanzee Pan troglodytes XP_509535 1209 138911 S983 E N L P E E D S E E E E E G G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538233 1446 163698 E1214 P P E G E S D E D A E K D E N
Cat Felis silvestris
Mouse Mus musculus Q9R1X4 1197 137484 E979 H L P E D E S E D E E S E E G
Rat Rattus norvegicus Q9Z2Y1 1205 138547 E981 K E G L P E S E G E E N E E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512607 1213 138721 E965 E E E E E S E E E E E E E P E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922924 1278 147885 D978 E D D D E D D D D K S D Q D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524341 1384 159345 D988 A E E P M F E D Q G Y K K P K
Honey Bee Apis mellifera XP_623203 520 60789 T355 L I A M D Q S T D R G I R E S
Nematode Worm Caenorhab. elegans NP_499594 1353 156992 R1157 K P T R Q V E R H L E S L G A
Sea Urchin Strong. purpuratus XP_784350 1529 176104 S1029 N D G D E E N S D E E E E E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 73.6 N.A. 83.8 81.4 N.A. 70.2 N.A. N.A. 59.5 N.A. 33.1 20.3 23.2 38
Protein Similarity: 100 99.7 N.A. 77.9 N.A. 90.5 89.6 N.A. 80.4 N.A. N.A. 73.6 N.A. 53 30.7 43 55.7
P-Site Identity: 100 100 N.A. 20 N.A. 33.3 26.6 N.A. 46.6 N.A. N.A. 20 N.A. 6.6 0 13.3 53.3
P-Site Similarity: 100 100 N.A. 40 N.A. 46.6 33.3 N.A. 53.3 N.A. N.A. 60 N.A. 33.3 26.6 33.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 0 0 0 10 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 10 19 19 10 37 19 46 0 0 10 10 10 10 % D
% Glu: 37 28 28 19 55 46 28 37 28 55 73 37 55 46 19 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 19 10 0 0 0 0 10 10 10 0 0 28 37 % G
% His: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 19 0 0 0 0 0 0 0 0 10 0 19 10 0 10 % K
% Leu: 10 10 19 10 0 0 0 0 0 10 0 0 10 0 0 % L
% Met: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 19 0 0 0 0 10 0 0 0 0 10 0 0 10 % N
% Pro: 10 19 10 28 10 0 0 0 0 0 0 0 0 19 0 % P
% Gln: 0 0 0 0 10 10 0 0 10 0 0 0 10 0 0 % Q
% Arg: 0 0 0 10 0 0 0 10 0 10 0 0 10 0 0 % R
% Ser: 0 0 0 0 0 19 28 28 0 0 10 19 0 0 10 % S
% Thr: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _