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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIMELESS
All Species:
12.73
Human Site:
S580
Identified Species:
28
UniProt:
Q9UNS1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNS1
NP_003911.2
1208
138630
S580
N
S
E
L
S
M
D
S
V
V
P
F
D
A
A
Chimpanzee
Pan troglodytes
XP_509535
1209
138911
S580
N
S
E
L
S
M
D
S
V
V
P
F
D
A
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538233
1446
163698
S808
D
P
D
L
S
L
D
S
V
V
P
F
D
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1X4
1197
137484
P576
D
P
E
L
S
V
D
P
V
V
P
F
D
A
A
Rat
Rattus norvegicus
Q9Z2Y1
1205
138547
S576
E
P
E
L
S
V
D
S
I
I
P
F
D
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512607
1213
138721
D575
D
P
V
L
P
A
D
D
V
V
P
F
D
A
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922924
1278
147885
G574
L
P
E
S
L
T
E
G
A
V
P
F
D
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524341
1384
159345
Q580
L
E
M
P
E
D
E
Q
P
L
P
F
D
A
A
Honey Bee
Apis mellifera
XP_623203
520
60789
L26
Y
D
G
S
K
Y
H
L
D
K
H
C
L
D
V
Nematode Worm
Caenorhab. elegans
NP_499594
1353
156992
G579
K
E
V
P
E
M
R
G
M
N
P
I
D
S
Q
Sea Urchin
Strong. purpuratus
XP_784350
1529
176104
D587
G
R
E
D
V
P
D
D
V
V
P
F
D
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.6
N.A.
83.8
81.4
N.A.
70.2
N.A.
N.A.
59.5
N.A.
33.1
20.3
23.2
38
Protein Similarity:
100
99.7
N.A.
77.9
N.A.
90.5
89.6
N.A.
80.4
N.A.
N.A.
73.6
N.A.
53
30.7
43
55.7
P-Site Identity:
100
100
N.A.
73.3
N.A.
73.3
66.6
N.A.
60
N.A.
N.A.
46.6
N.A.
33.3
0
20
60
P-Site Similarity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
66.6
N.A.
N.A.
53.3
N.A.
46.6
0
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
10
0
0
0
0
82
82
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
28
10
10
10
0
10
64
19
10
0
0
0
91
10
0
% D
% Glu:
10
19
55
0
19
0
19
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
82
0
0
0
% F
% Gly:
10
0
10
0
0
0
0
19
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
10
0
10
0
0
0
% I
% Lys:
10
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
19
0
0
55
10
10
0
10
0
10
0
0
10
0
0
% L
% Met:
0
0
10
0
0
28
0
0
10
0
0
0
0
0
0
% M
% Asn:
19
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
46
0
19
10
10
0
10
10
0
91
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% Q
% Arg:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
19
0
19
46
0
0
37
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
19
0
10
19
0
0
55
64
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _