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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIMELESS
All Species:
18.18
Human Site:
S309
Identified Species:
40
UniProt:
Q9UNS1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNS1
NP_003911.2
1208
138630
S309
H
N
L
R
N
Y
S
S
D
L
G
K
Q
P
K
Chimpanzee
Pan troglodytes
XP_509535
1209
138911
S309
H
N
L
R
N
Y
S
S
D
L
G
K
Q
P
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538233
1446
163698
S538
H
N
L
Q
N
Y
S
S
D
L
G
K
Q
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1X4
1197
137484
S309
H
N
L
Q
N
Y
S
S
D
L
G
K
Q
P
R
Rat
Rattus norvegicus
Q9Z2Y1
1205
138547
S309
H
N
L
Q
N
Y
S
S
D
L
G
K
Q
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512607
1213
138721
P304
H
N
F
Q
N
Y
S
P
D
M
V
K
E
V
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922924
1278
147885
H309
H
N
F
K
S
Y
S
H
D
L
G
K
A
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524341
1384
159345
F306
E
R
V
S
S
I
D
F
D
R
E
K
Q
Q
Q
Honey Bee
Apis mellifera
XP_623203
520
60789
Nematode Worm
Caenorhab. elegans
NP_499594
1353
156992
F303
Q
N
V
E
K
H
N
F
L
D
D
R
K
A
K
Sea Urchin
Strong. purpuratus
XP_784350
1529
176104
K318
T
M
T
F
E
S
T
K
N
A
T
K
K
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.6
N.A.
83.8
81.4
N.A.
70.2
N.A.
N.A.
59.5
N.A.
33.1
20.3
23.2
38
Protein Similarity:
100
99.7
N.A.
77.9
N.A.
90.5
89.6
N.A.
80.4
N.A.
N.A.
73.6
N.A.
53
30.7
43
55.7
P-Site Identity:
100
100
N.A.
86.6
N.A.
86.6
86.6
N.A.
46.6
N.A.
N.A.
53.3
N.A.
20
0
13.3
20
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
73.3
N.A.
N.A.
73.3
N.A.
40
0
46.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
73
10
10
0
0
0
0
% D
% Glu:
10
0
0
10
10
0
0
0
0
0
10
0
10
0
0
% E
% Phe:
0
0
19
10
0
0
0
19
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
55
0
0
0
0
% G
% His:
64
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
0
10
0
0
0
82
19
0
37
% K
% Leu:
0
0
46
0
0
0
0
0
10
55
0
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
73
0
0
55
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
55
0
% P
% Gln:
10
0
0
37
0
0
0
0
0
0
0
0
55
10
10
% Q
% Arg:
0
10
0
19
0
0
0
0
0
10
0
10
0
0
46
% R
% Ser:
0
0
0
10
19
10
64
46
0
0
0
0
0
0
0
% S
% Thr:
10
0
10
0
0
0
10
0
0
0
10
0
0
0
0
% T
% Val:
0
0
19
0
0
0
0
0
0
0
10
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
64
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _