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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIE All Species: 36.06
Human Site: S97 Identified Species: 52.89
UniProt: Q9UNP9 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNP9 NP_982281.1 301 33431 S97 G S S R P V W S D D D W L K K
Chimpanzee Pan troglodytes XP_001171465 296 32995 S97 G S S R P V W S D D D W L K K
Rhesus Macaque Macaca mulatta XP_001113613 301 33370 S97 G S S R P V W S D D D W L K K
Dog Lupus familis XP_848739 301 33398 S97 G S S R P V W S D D D W L K K
Cat Felis silvestris
Mouse Mus musculus Q9QZH3 301 33430 S97 G S S R P V W S D D D W L K K
Rat Rattus norvegicus P29117 206 21791 L10 A L R C G P R L L G L L S G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515609 324 35644 S97 G S S R P V W S D D E W L K K
Chicken Gallus gallus XP_423739 301 33300 S97 G S S R P V W S D D E W L K R
Frog Xenopus laevis NP_001090502 294 32711 S90 G S S K A V W S D D D W L K K
Zebra Danio Brachydanio rerio NP_001017678 302 33478 S97 G S S R P V W S D D D W L K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3G3 300 33258 A97 D S F K P I W A D D D W L Q K
Honey Bee Apis mellifera XP_623848 293 32390 K89 I A K P Q K I K E G S S K P V
Nematode Worm Caenorhab. elegans P52015 171 18382
Sea Urchin Strong. purpuratus XP_799104 292 32038 K88 V N L A K P M K I K D G S A K
Poplar Tree Populus trichocarpa
Maize Zea mays P21569 172 18330
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SKQ0 174 18445
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.6 99.6 99.3 N.A. 98.3 42.8 N.A. 87.3 91.6 86 86.7 N.A. 64.7 71.4 37.8 73.4
Protein Similarity: 100 94.3 99.6 99.3 N.A. 99 54.4 N.A. 91.3 96.6 91.6 94 N.A. 79.4 83.3 46.5 85
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 93.3 86.6 86.6 100 N.A. 60 0 0 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 0 N.A. 100 100 93.3 100 N.A. 86.6 13.3 0 20
Percent
Protein Identity: N.A. 33.5 N.A. 40.2 N.A. N.A.
Protein Similarity: N.A. 44.8 N.A. 46.5 N.A. N.A.
P-Site Identity: N.A. 0 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 0 N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 7 7 0 0 7 0 0 0 0 0 7 0 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 63 63 57 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 7 0 13 0 0 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 57 0 0 0 7 0 0 0 0 13 0 7 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 7 7 0 7 0 0 0 0 0 0 % I
% Lys: 0 0 7 13 7 7 0 13 0 7 0 0 7 57 63 % K
% Leu: 0 7 7 0 0 0 0 7 7 0 7 7 63 0 0 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 7 57 13 0 0 0 0 0 0 0 7 7 % P
% Gln: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % Q
% Arg: 0 0 7 50 0 0 7 0 0 0 0 0 0 0 7 % R
% Ser: 0 63 57 0 0 0 0 57 0 0 7 7 13 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 7 0 0 0 0 57 0 0 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 63 0 0 0 0 63 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _