Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIE All Species: 38.18
Human Site: S283 Identified Species: 56
UniProt: Q9UNP9 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNP9 NP_982281.1 301 33431 S283 R Q I E A Q G S K D G K P K Q
Chimpanzee Pan troglodytes XP_001171465 296 32995 I278 G L D V L R Q I E K Q G E S A
Rhesus Macaque Macaca mulatta XP_001113613 301 33370 S283 R Q I E A Q G S K D G K P K Q
Dog Lupus familis XP_848739 301 33398 S283 R Q I E A Q G S K D G K P K Q
Cat Felis silvestris
Mouse Mus musculus Q9QZH3 301 33430 S283 R Q I E A Q G S K D G K P K Q
Rat Rattus norvegicus P29117 206 21791 G191 E S F G S K S G K T S K K I V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515609 324 35644 S282 R Q I E A Q G S K D G K P K Q
Chicken Gallus gallus XP_423739 301 33300 T283 R Q I E A Q G T K E G K P K Q
Frog Xenopus laevis NP_001090502 294 32711 G276 R Q M E A Q G G K D G K P K Q
Zebra Danio Brachydanio rerio NP_001017678 302 33478 T284 R A M E A Q G T K D G K P K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3G3 300 33258 S282 R K M E R C G S K S G T P S Q
Honey Bee Apis mellifera XP_623848 293 32390 T275 K K I E K C G T K S G I P I Q
Nematode Worm Caenorhab. elegans P52015 171 18382 S156 V E G N G S S S G T P K S E C
Sea Urchin Strong. purpuratus XP_799104 292 32038 T274 K K M E S V G T K S G K P R E
Poplar Tree Populus trichocarpa
Maize Zea mays P21569 172 18330 G157 E K V G T R N G S T S K V V K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SKQ0 174 18445 K159 K I G S S S G K P T K P V V I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.6 99.6 99.3 N.A. 98.3 42.8 N.A. 87.3 91.6 86 86.7 N.A. 64.7 71.4 37.8 73.4
Protein Similarity: 100 94.3 99.6 99.3 N.A. 99 54.4 N.A. 91.3 96.6 91.6 94 N.A. 79.4 83.3 46.5 85
P-Site Identity: 100 0 100 100 N.A. 100 13.3 N.A. 100 86.6 86.6 80 N.A. 53.3 46.6 13.3 40
P-Site Similarity: 100 13.3 100 100 N.A. 100 26.6 N.A. 100 100 93.3 93.3 N.A. 66.6 66.6 26.6 86.6
Percent
Protein Identity: N.A. 33.5 N.A. 40.2 N.A. N.A.
Protein Similarity: N.A. 44.8 N.A. 46.5 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 50 0 0 0 0 0 0 0 0 0 7 % A
% Cys: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 0 7 0 0 0 0 0 0 44 0 0 0 0 0 % D
% Glu: 13 7 0 69 0 0 0 0 7 7 0 0 7 7 7 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 13 13 7 0 75 19 7 0 69 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 44 0 0 0 0 7 0 0 0 7 0 13 7 % I
% Lys: 19 25 0 0 7 7 0 7 75 7 7 75 7 50 7 % K
% Leu: 0 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 25 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 7 0 7 7 69 0 0 % P
% Gln: 0 44 0 0 0 50 7 0 0 0 7 0 0 0 63 % Q
% Arg: 57 0 0 0 7 13 0 0 0 0 0 0 0 7 0 % R
% Ser: 0 7 0 7 19 13 13 44 7 19 13 0 7 13 0 % S
% Thr: 0 0 0 0 7 0 0 25 0 25 0 7 0 0 0 % T
% Val: 7 0 7 7 0 7 0 0 0 0 0 0 13 13 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _