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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIE All Species: 17.27
Human Site: S138 Identified Species: 25.33
UniProt: Q9UNP9 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNP9 NP_982281.1 301 33431 S138 P I A K K A R S N P Q V Y M D
Chimpanzee Pan troglodytes XP_001171465 296 32995 S138 P I A K K A R S N P Q V Y M D
Rhesus Macaque Macaca mulatta XP_001113613 301 33370 S138 P A A K K A R S N P Q V Y M D
Dog Lupus familis XP_848739 301 33398 S138 P A A K K A R S N P Q V Y M D
Cat Felis silvestris
Mouse Mus musculus Q9QZH3 301 33430 S138 P T A K K A R S N P Q V Y M D
Rat Rattus norvegicus P29117 206 21791 V51 N P L V Y L D V G A D G Q P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515609 324 35644 N138 P A K K A R A N P Q V Y M D I
Chicken Gallus gallus XP_423739 301 33300 A138 P P A K K S R A N P Q V Y M D
Frog Xenopus laevis NP_001090502 294 32711 A131 P P P K K V R A N P Q V Y M D
Zebra Danio Brachydanio rerio NP_001017678 302 33478 R138 E P P A K K G R T N P Q V Y M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3G3 300 33258 N138 I E K A E K R N P Q V F F D I
Honey Bee Apis mellifera XP_623848 293 32390 Q130 V Q P K K G K Q N P Q V Y F D
Nematode Worm Caenorhab. elegans P52015 171 18382 P16 D I T I A G K P T G R I V M E
Sea Urchin Strong. purpuratus XP_799104 292 32038 A129 P A P K K S K A N S Q V F F D
Poplar Tree Populus trichocarpa
Maize Zea mays P21569 172 18330 A17 M T V G G A P A G R I V M E L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SKQ0 174 18445 G19 T I G G A P A G K I V M E L Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.6 99.6 99.3 N.A. 98.3 42.8 N.A. 87.3 91.6 86 86.7 N.A. 64.7 71.4 37.8 73.4
Protein Similarity: 100 94.3 99.6 99.3 N.A. 99 54.4 N.A. 91.3 96.6 91.6 94 N.A. 79.4 83.3 46.5 85
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 0 N.A. 13.3 80 73.3 6.6 N.A. 6.6 53.3 13.3 46.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 0 N.A. 20 93.3 80 6.6 N.A. 26.6 60 40 73.3
Percent
Protein Identity: N.A. 33.5 N.A. 40.2 N.A. N.A.
Protein Similarity: N.A. 44.8 N.A. 46.5 N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 20 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 38 13 19 38 13 25 0 7 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 7 0 0 0 7 0 0 13 57 % D
% Glu: 7 7 0 0 7 0 0 0 0 0 0 0 7 7 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 7 13 13 0 % F
% Gly: 0 0 7 13 7 13 7 7 13 7 0 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 25 0 7 0 0 0 0 0 7 7 7 0 0 13 % I
% Lys: 0 0 13 63 63 13 19 0 7 0 0 0 0 0 0 % K
% Leu: 0 0 7 0 0 7 0 0 0 0 0 0 0 7 13 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 7 13 50 7 % M
% Asn: 7 0 0 0 0 0 0 13 57 7 0 0 0 0 0 % N
% Pro: 57 25 25 0 0 7 7 7 13 50 7 0 0 7 0 % P
% Gln: 0 7 0 0 0 0 0 7 0 13 57 7 7 0 0 % Q
% Arg: 0 0 0 0 0 7 50 7 0 7 7 0 0 0 0 % R
% Ser: 0 0 0 0 0 13 0 32 0 7 0 0 0 0 0 % S
% Thr: 7 13 7 0 0 0 0 0 13 0 0 0 0 0 0 % T
% Val: 7 0 7 7 0 7 0 7 0 0 19 63 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 7 50 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _