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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STX8 All Species: 33.64
Human Site: S96 Identified Species: 52.86
UniProt: Q9UNK0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNK0 NP_004844.1 236 26907 S96 R E R L L L A S F K N E G A E
Chimpanzee Pan troglodytes XP_001165617 217 24883 S96 R E R L L L A S F K N E G A E
Rhesus Macaque Macaca mulatta XP_001113412 236 26871 S96 R E R L L L A S F K N E G A E
Dog Lupus familis XP_536638 236 26711 S96 R E R L L V A S F K N E G A E
Cat Felis silvestris
Mouse Mus musculus O88983 236 26906 S96 R E R L L L A S F K N E G A E
Rat Rattus norvegicus Q9Z2Q7 236 26892 S96 R E R L L L A S F K N E G S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511960 437 48270 S237 R E R Q L Q A S Y K R E S A E
Chicken Gallus gallus Q5ZL19 254 29137 T95 R K S F I T S T R Q V V R E M
Frog Xenopus laevis NP_001090074 236 26877 S96 K E Q Q L Q M S F K R E G V E
Zebra Danio Brachydanio rerio NP_956669 235 26077 S96 R E T R L N A S F K G D I T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524113 232 26466 E98 S Q L R E I R E K F A N S S R
Honey Bee Apis mellifera XP_624480 239 27451 L102 R D V H L Q E L C D A R T N N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799247 172 19687 D71 H L T Q R E A D R R R A L V D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SA23 232 25870 A104 A L N M S N F A N R D S L L G
Baker's Yeast Sacchar. cerevisiae P31377 255 29030 P126 Q D E E S P L P S T H T P Y K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 98.3 91.9 N.A. 92.8 92.8 N.A. 33.1 21.6 66.9 57.2 N.A. 26.6 29.2 N.A. 30
Protein Similarity: 100 91 99.1 94.4 N.A. 94.9 95.3 N.A. 39.5 44.8 82.1 74.1 N.A. 53.3 49.7 N.A. 46.1
P-Site Identity: 100 100 100 93.3 N.A. 100 93.3 N.A. 66.6 6.6 53.3 53.3 N.A. 0 13.3 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 73.3 40 66.6 60 N.A. 20 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 23.7 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. 47 41.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 0 60 7 0 0 14 7 0 40 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 14 0 0 0 0 0 7 0 7 7 7 0 0 7 % D
% Glu: 0 60 7 7 7 7 7 7 0 0 0 54 0 7 60 % E
% Phe: 0 0 0 7 0 0 7 0 54 7 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 7 0 47 0 7 % G
% His: 7 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % H
% Ile: 0 0 0 0 7 7 0 0 0 0 0 0 7 0 0 % I
% Lys: 7 7 0 0 0 0 0 0 7 60 0 0 0 0 7 % K
% Leu: 0 14 7 40 67 34 7 7 0 0 0 0 14 7 0 % L
% Met: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 7 0 0 14 0 0 7 0 40 7 0 7 7 % N
% Pro: 0 0 0 0 0 7 0 7 0 0 0 0 7 0 0 % P
% Gln: 7 7 7 20 0 20 0 0 0 7 0 0 0 0 0 % Q
% Arg: 67 0 47 14 7 0 7 0 14 14 20 7 7 0 7 % R
% Ser: 7 0 7 0 14 0 7 60 7 0 0 7 14 14 0 % S
% Thr: 0 0 14 0 0 7 0 7 0 7 0 7 7 7 0 % T
% Val: 0 0 7 0 0 7 0 0 0 0 7 7 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _