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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUSP12 All Species: 23.64
Human Site: Y303 Identified Species: 37.14
UniProt: Q9UNI6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNI6 NP_009171.1 340 37687 Y303 K L G S F N W Y G E Q C S C G
Chimpanzee Pan troglodytes XP_514446 364 39904 Y327 K L G S F N W Y G E Q C S C G
Rhesus Macaque Macaca mulatta XP_001118147 340 37885 Y303 K L G S F N W Y G E Q C S C G
Dog Lupus familis XP_536142 339 37199 Y302 K L G S F N W Y G E Q C S C G
Cat Felis silvestris
Mouse Mus musculus Q9D0T2 339 37140 Y302 K L G S F N W Y G E Q C S C G
Rat Rattus norvegicus Q9JIM4 339 37178 Y302 K L G S F N W Y G E Q C S C G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423122 309 33303 W272 K L G S F S W W G E Q C S C G
Frog Xenopus laevis Q6GQJ8 209 23467 E179 H K Q Q E A A E S Q N A T S S
Zebra Danio Brachydanio rerio Q566R7 183 20613 E153 F R E W L K E E Y K E N P F N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608332 387 43724 I352 K L G N F S W I N A C K C P C
Honey Bee Apis mellifera XP_396430 347 39479 I312 K L G F F S W I A G S Q C P C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203068 264 29514 S234 H K H K G Q M S K E Q G S I S
Poplar Tree Populus trichocarpa XP_002308890 352 39035 G321 A H C E A R L G Y F N W S G I
Maize Zea mays NP_001130071 354 39026 G323 I H C G A R L G Y F N W S G I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02256 364 41167 K320 K V G G Y N W K G S R C S C G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.4 96.1 85.2 N.A. 83.5 82.6 N.A. N.A. 58.5 20.8 21.7 N.A. 31.7 31.9 N.A. 26.4
Protein Similarity: 100 93.4 96.4 89.1 N.A. 89.7 89.1 N.A. N.A. 70.5 36.1 33.5 N.A. 48.5 49.8 N.A. 43.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 86.6 0 0 N.A. 33.3 33.3 N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 13.3 13.3 N.A. 46.6 40 N.A. 20
Percent
Protein Identity: 37.2 34.7 N.A. N.A. 26.6 N.A.
Protein Similarity: 55.4 51.9 N.A. N.A. 46.9 N.A.
P-Site Identity: 6.6 6.6 N.A. N.A. 60 N.A.
P-Site Similarity: 6.6 6.6 N.A. N.A. 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 14 7 7 0 7 7 0 7 0 0 0 % A
% Cys: 0 0 14 0 0 0 0 0 0 0 7 54 14 54 14 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 7 7 7 0 7 14 0 54 7 0 0 0 0 % E
% Phe: 7 0 0 7 60 0 0 0 0 14 0 0 0 7 0 % F
% Gly: 0 0 67 14 7 0 0 14 54 7 0 7 0 14 54 % G
% His: 14 14 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 0 14 0 0 0 0 0 7 14 % I
% Lys: 67 14 0 7 0 7 0 7 7 7 0 7 0 0 0 % K
% Leu: 0 60 0 0 7 0 14 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 0 47 0 0 7 0 20 7 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 7 14 0 % P
% Gln: 0 0 7 7 0 7 0 0 0 7 54 7 0 0 0 % Q
% Arg: 0 7 0 0 0 14 0 0 0 0 7 0 0 0 0 % R
% Ser: 0 0 0 47 0 20 0 7 7 7 7 0 74 7 14 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % T
% Val: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 7 0 0 67 7 0 0 0 14 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 40 20 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _