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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP12
All Species:
25.45
Human Site:
Y268
Identified Species:
40
UniProt:
Q9UNI6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNI6
NP_009171.1
340
37687
Y268
R
Q
A
Q
C
T
S
Y
F
I
E
P
V
Q
W
Chimpanzee
Pan troglodytes
XP_514446
364
39904
Y292
R
Q
A
Q
C
T
S
Y
F
I
E
P
V
Q
W
Rhesus Macaque
Macaca mulatta
XP_001118147
340
37885
Y268
R
Q
A
Q
C
T
S
Y
F
I
E
P
V
Q
W
Dog
Lupus familis
XP_536142
339
37199
Y267
S
Q
A
Q
C
T
S
Y
F
I
E
P
V
Q
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0T2
339
37140
Y267
S
Q
A
Q
C
T
S
Y
F
I
E
P
V
Q
W
Rat
Rattus norvegicus
Q9JIM4
339
37178
Y267
N
Q
A
Q
C
T
S
Y
F
I
E
P
V
Q
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423122
309
33303
Y237
G
P
D
K
C
T
S
Y
F
I
E
P
V
Q
W
Frog
Xenopus laevis
Q6GQJ8
209
23467
H145
F
G
K
C
E
V
H
H
F
R
T
W
L
K
D
Zebra Danio
Brachydanio rerio
Q566R7
183
20613
K119
Q
E
A
L
A
A
V
K
I
A
R
P
C
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608332
387
43724
A281
P
A
Q
S
H
D
Q
A
E
N
H
H
G
A
R
Honey Bee
Apis mellifera
XP_396430
347
39479
Q264
H
E
L
L
E
P
L
Q
K
E
E
Q
Q
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203068
264
29514
R200
D
N
T
L
Y
K
C
R
K
C
R
R
A
L
F
Poplar Tree
Populus trichocarpa
XP_002308890
352
39035
N281
Q
K
S
G
N
P
L
N
K
S
D
E
S
E
C
Maize
Zea mays
NP_001130071
354
39026
N285
K
S
G
H
P
Y
N
N
K
E
H
G
C
S
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02256
364
41167
F283
S
Q
A
N
C
S
H
F
F
I
E
P
L
K
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
96.1
85.2
N.A.
83.5
82.6
N.A.
N.A.
58.5
20.8
21.7
N.A.
31.7
31.9
N.A.
26.4
Protein Similarity:
100
93.4
96.4
89.1
N.A.
89.7
89.1
N.A.
N.A.
70.5
36.1
33.5
N.A.
48.5
49.8
N.A.
43.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
73.3
6.6
13.3
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
26.6
26.6
N.A.
0
13.3
N.A.
6.6
Percent
Protein Identity:
37.2
34.7
N.A.
N.A.
26.6
N.A.
Protein Similarity:
55.4
51.9
N.A.
N.A.
46.9
N.A.
P-Site Identity:
0
0
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
33.3
13.3
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
54
0
7
7
0
7
0
7
0
0
7
14
0
% A
% Cys:
0
0
0
7
54
0
7
0
0
7
0
0
14
0
7
% C
% Asp:
7
0
7
0
0
7
0
0
0
0
7
0
0
0
7
% D
% Glu:
0
14
0
0
14
0
0
0
7
14
60
7
0
7
0
% E
% Phe:
7
0
0
0
0
0
0
7
60
0
0
0
0
0
7
% F
% Gly:
7
7
7
7
0
0
0
0
0
0
0
7
7
0
0
% G
% His:
7
0
0
7
7
0
14
7
0
0
14
7
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
54
0
0
0
0
0
% I
% Lys:
7
7
7
7
0
7
0
7
27
0
0
0
0
14
0
% K
% Leu:
0
0
7
20
0
0
14
0
0
0
0
0
14
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
7
7
0
7
14
0
7
0
0
0
0
0
% N
% Pro:
7
7
0
0
7
14
0
0
0
0
0
60
0
0
0
% P
% Gln:
14
47
7
40
0
0
7
7
0
0
0
7
7
47
0
% Q
% Arg:
20
0
0
0
0
0
0
7
0
7
14
7
0
0
7
% R
% Ser:
20
7
7
7
0
7
47
0
0
7
0
0
7
14
14
% S
% Thr:
0
0
7
0
0
47
0
0
0
0
7
0
0
0
0
% T
% Val:
0
0
0
0
0
7
7
0
0
0
0
0
47
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
54
% W
% Tyr:
0
0
0
0
7
7
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _