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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP12
All Species:
19.09
Human Site:
T258
Identified Species:
30
UniProt:
Q9UNI6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNI6
NP_009171.1
340
37687
T258
M
T
P
S
S
M
L
T
T
G
R
Q
A
Q
C
Chimpanzee
Pan troglodytes
XP_514446
364
39904
T282
M
T
P
S
S
M
L
T
T
G
R
Q
A
Q
C
Rhesus Macaque
Macaca mulatta
XP_001118147
340
37885
T258
M
T
S
S
F
M
L
T
T
G
R
Q
A
Q
C
Dog
Lupus familis
XP_536142
339
37199
T257
V
T
P
S
F
T
L
T
T
G
S
Q
A
Q
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0T2
339
37140
T257
T
A
P
S
S
V
L
T
T
G
S
Q
A
Q
C
Rat
Rattus norvegicus
Q9JIM4
339
37178
T257
T
G
L
S
S
V
L
T
T
G
N
Q
A
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423122
309
33303
R227
I
T
E
S
T
H
L
R
G
S
G
P
D
K
C
Frog
Xenopus laevis
Q6GQJ8
209
23467
L135
N
M
G
F
Q
K
Q
L
E
D
F
G
K
C
E
Zebra Danio
Brachydanio rerio
Q566R7
183
20613
L109
Y
I
M
T
V
T
T
L
G
W
Q
E
A
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608332
387
43724
A271
E
K
E
E
V
A
A
A
K
L
P
A
Q
S
H
Honey Bee
Apis mellifera
XP_396430
347
39479
K254
R
K
T
S
K
Q
S
K
P
S
H
E
L
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203068
264
29514
P190
P
A
S
S
S
P
N
P
A
G
D
N
T
L
Y
Poplar Tree
Populus trichocarpa
XP_002308890
352
39035
W271
E
G
E
T
S
F
A
W
S
K
Q
K
S
G
N
Maize
Zea mays
NP_001130071
354
39026
N275
G
E
S
C
F
D
W
N
R
R
K
S
G
H
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02256
364
41167
I273
N
S
H
R
I
I
D
I
Q
E
S
Q
A
N
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
96.1
85.2
N.A.
83.5
82.6
N.A.
N.A.
58.5
20.8
21.7
N.A.
31.7
31.9
N.A.
26.4
Protein Similarity:
100
93.4
96.4
89.1
N.A.
89.7
89.1
N.A.
N.A.
70.5
36.1
33.5
N.A.
48.5
49.8
N.A.
43.8
P-Site Identity:
100
100
86.6
73.3
N.A.
73.3
66.6
N.A.
N.A.
26.6
0
6.6
N.A.
0
6.6
N.A.
20
P-Site Similarity:
100
100
86.6
80
N.A.
80
73.3
N.A.
N.A.
46.6
0
26.6
N.A.
0
13.3
N.A.
20
Percent
Protein Identity:
37.2
34.7
N.A.
N.A.
26.6
N.A.
Protein Similarity:
55.4
51.9
N.A.
N.A.
46.9
N.A.
P-Site Identity:
6.6
0
N.A.
N.A.
20
N.A.
P-Site Similarity:
40
6.6
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
0
7
14
7
7
0
0
7
54
0
7
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
54
% C
% Asp:
0
0
0
0
0
7
7
0
0
7
7
0
7
0
0
% D
% Glu:
14
7
20
7
0
0
0
0
7
7
0
14
0
0
14
% E
% Phe:
0
0
0
7
20
7
0
0
0
0
7
0
0
0
0
% F
% Gly:
7
14
7
0
0
0
0
0
14
47
7
7
7
7
0
% G
% His:
0
0
7
0
0
7
0
0
0
0
7
0
0
7
7
% H
% Ile:
7
7
0
0
7
7
0
7
0
0
0
0
0
0
0
% I
% Lys:
0
14
0
0
7
7
0
7
7
7
7
7
7
7
0
% K
% Leu:
0
0
7
0
0
0
47
14
0
7
0
0
7
20
0
% L
% Met:
20
7
7
0
0
20
0
0
0
0
0
0
0
0
0
% M
% Asn:
14
0
0
0
0
0
7
7
0
0
7
7
0
7
7
% N
% Pro:
7
0
27
0
0
7
0
7
7
0
7
7
0
0
7
% P
% Gln:
0
0
0
0
7
7
7
0
7
0
14
47
7
40
0
% Q
% Arg:
7
0
0
7
0
0
0
7
7
7
20
0
0
0
0
% R
% Ser:
0
7
20
60
40
0
7
0
7
14
20
7
7
7
0
% S
% Thr:
14
34
7
14
7
14
7
40
40
0
0
0
7
0
0
% T
% Val:
7
0
0
0
14
14
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
7
7
0
7
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _