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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC6A14
All Species:
11.52
Human Site:
S381
Identified Species:
21.11
UniProt:
Q9UN76
Number Species:
12
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UN76
NP_009162.1
642
72153
S381
H
I
S
G
K
E
V
S
Q
V
V
K
S
G
F
Chimpanzee
Pan troglodytes
XP_521869
797
87347
E536
N
E
R
K
V
N
I
E
N
V
A
D
Q
G
P
Rhesus Macaque
Macaca mulatta
Q9MYX0
630
70239
S395
E
M
R
N
E
D
V
S
E
V
A
K
D
A
G
Dog
Lupus familis
XP_549207
639
71865
S378
H
I
S
G
K
E
V
S
Q
V
V
K
S
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMA9
638
71437
S377
H
I
S
G
K
E
V
S
Q
V
V
K
S
G
F
Rat
Rattus norvegicus
P58295
799
87890
E538
N
E
R
K
V
N
I
E
N
V
A
D
Q
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520986
579
64733
M370
F
P
K
L
M
K
T
M
R
V
P
V
T
L
G
Chicken
Gallus gallus
XP_420906
854
94085
E593
N
E
L
K
V
N
I
E
A
V
A
D
Q
G
P
Frog
Xenopus laevis
A7Y2X0
790
87434
E529
H
I
L
N
V
D
I
E
K
V
A
D
Q
G
P
Zebra Danio
Brachydanio rerio
XP_001923596
614
68214
P381
L
S
K
L
P
I
S
P
L
W
S
I
L
F
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51905
622
69307
D387
Y
V
Q
K
T
S
I
D
K
V
G
L
E
G
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03614
615
69247
E373
C
K
S
G
K
P
I
E
A
V
A
Q
E
G
P
Sea Urchin
Strong. purpuratus
XP_001179122
659
73488
A383
Q
A
Q
G
K
E
V
A
D
V
I
D
S
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.9
40.3
93.4
N.A.
88.9
42.1
N.A.
75.5
39.2
41.6
61
N.A.
39.4
N.A.
36.2
48.4
Protein Similarity:
100
56.4
58.2
97.3
N.A.
95.3
55.3
N.A.
80.8
52.2
56.3
75.6
N.A.
57.9
N.A.
55.4
64.3
P-Site Identity:
100
13.3
26.6
100
N.A.
100
13.3
N.A.
6.6
13.3
26.6
6.6
N.A.
13.3
N.A.
33.3
53.3
P-Site Similarity:
100
26.6
53.3
100
N.A.
100
26.6
N.A.
26.6
26.6
46.6
6.6
N.A.
40
N.A.
46.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
16
0
47
0
0
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
16
0
8
8
0
0
39
8
0
0
% D
% Glu:
8
24
0
0
8
31
0
39
8
0
0
0
16
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
39
% F
% Gly:
0
0
0
39
0
0
0
0
0
0
8
0
0
77
16
% G
% His:
31
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
31
0
0
0
8
47
0
0
0
8
8
0
0
0
% I
% Lys:
0
8
16
31
39
8
0
0
16
0
0
31
0
0
0
% K
% Leu:
8
0
16
16
0
0
0
0
8
0
0
8
8
8
0
% L
% Met:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
24
0
0
16
0
24
0
0
16
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
8
8
0
8
0
0
8
0
0
0
47
% P
% Gln:
8
0
16
0
0
0
0
0
24
0
0
8
31
0
0
% Q
% Arg:
0
0
24
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
8
31
0
0
8
8
31
0
0
8
0
31
0
0
% S
% Thr:
0
0
0
0
8
0
8
0
0
0
0
0
8
0
0
% T
% Val:
0
8
0
0
31
0
39
0
0
93
24
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _