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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPX2 All Species: 25.76
Human Site: T338 Identified Species: 56.67
UniProt: Q9ULW0 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULW0 NP_036244.2 747 85653 T338 V E D F H K R T P N R Y H L R
Chimpanzee Pan troglodytes XP_001153533 746 85517 T337 V E D F H K R T P N R Y H L R
Rhesus Macaque Macaca mulatta XP_001109645 746 85683 T337 V E D F H K R T P N R Y H L R
Dog Lupus familis XP_850934 748 86144 T339 V E A F H K R T P N R Y H L R
Cat Felis silvestris
Mouse Mus musculus NP_082385 745 85876 T340 V E A F H K R T P N R Y H L R
Rat Rattus norvegicus NP_001101260 744 85432 T338 V E A F H K R T P N R Y H L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516385 623 69684 V309 T K I L E D V V G V P Q K R Q
Chicken Gallus gallus NP_989768 739 85048 T337 V E A F Q K R T P S R Y H L R
Frog Xenopus laevis NP_001086751 715 81991 K318 Y H L R S R Q K E M E G P S P
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798362 948 108486 P538 Q Q F H N K T P Q R F H T R R
Poplar Tree Populus trichocarpa XP_002327911 811 91572 L346 F Q S N T R G L S M P R F N N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 97.5 90.3 N.A. 79.2 79.1 N.A. 40.1 57.5 53.8 N.A. N.A. N.A. N.A. N.A. 31.6
Protein Similarity: 100 99.3 98.6 93.9 N.A. 87.6 87.4 N.A. 53 72.5 70 N.A. N.A. N.A. N.A. N.A. 49.4
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 0 80 0 N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 13.3 86.6 13.3 N.A. N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: 20.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 39.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 37 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 28 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 64 0 0 10 0 0 0 10 0 10 0 0 0 0 % E
% Phe: 10 0 10 64 0 0 0 0 0 0 10 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 10 0 0 10 0 0 0 % G
% His: 0 10 0 10 55 0 0 0 0 0 0 10 64 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 73 0 10 0 0 0 0 10 0 0 % K
% Leu: 0 0 10 10 0 0 0 10 0 0 0 0 0 64 0 % L
% Met: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % M
% Asn: 0 0 0 10 10 0 0 0 0 55 0 0 0 10 10 % N
% Pro: 0 0 0 0 0 0 0 10 64 0 19 0 10 0 10 % P
% Gln: 10 19 0 0 10 0 10 0 10 0 0 10 0 0 10 % Q
% Arg: 0 0 0 10 0 19 64 0 0 10 64 10 0 19 73 % R
% Ser: 0 0 10 0 10 0 0 0 10 10 0 0 0 10 0 % S
% Thr: 10 0 0 0 10 0 10 64 0 0 0 0 10 0 0 % T
% Val: 64 0 0 0 0 0 10 10 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 64 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _