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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD4
All Species:
40.61
Human Site:
Y250
Identified Species:
81.21
UniProt:
Q9ULV1
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULV1
NP_036325.2
537
59881
Y250
I
D
S
S
R
F
S
Y
P
E
R
P
I
I
F
Chimpanzee
Pan troglodytes
XP_001175326
537
59849
Y250
I
D
S
S
R
F
S
Y
P
E
R
P
I
I
F
Rhesus Macaque
Macaca mulatta
XP_001103927
537
59890
Y250
I
D
S
S
R
F
S
Y
P
E
R
P
I
I
F
Dog
Lupus familis
XP_848753
541
60627
Y254
I
D
S
S
R
F
S
Y
P
E
R
P
I
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q61088
537
60125
Y250
I
D
S
S
R
F
S
Y
P
E
R
P
I
I
F
Rat
Rattus norvegicus
Q9QZH0
538
60336
Y251
I
D
S
S
R
F
S
Y
P
E
R
P
I
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511743
486
54161
Y211
I
I
F
L
S
M
C
Y
N
I
Y
S
V
A
Y
Chicken
Gallus gallus
Q9IA05
525
58747
Y238
I
D
S
S
R
F
S
Y
P
E
R
P
I
I
F
Frog
Xenopus laevis
Q9PT62
523
58722
Y236
I
D
S
S
R
F
C
Y
P
E
R
P
I
I
F
Zebra Danio
Brachydanio rerio
XP_002664771
455
51006
N180
I
F
L
S
M
C
C
N
I
Y
S
V
A
F
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
Y277
I
D
S
S
R
F
R
Y
P
E
R
A
I
V
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788346
818
91850
Y247
I
D
T
V
R
F
R
Y
P
E
R
P
I
I
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.8
97.9
N.A.
97
97.2
N.A.
83.4
93.3
89.3
70.7
N.A.
35.6
N.A.
N.A.
39.4
Protein Similarity:
100
100
100
98.1
N.A.
98.1
98.1
N.A.
87.5
95.3
93.3
76.1
N.A.
52.5
N.A.
N.A.
50.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
93.3
13.3
N.A.
80
N.A.
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
100
93.3
13.3
N.A.
86.6
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
9
9
9
0
% A
% Cys:
0
0
0
0
0
9
25
0
0
0
0
0
0
0
0
% C
% Asp:
0
84
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
0
% E
% Phe:
0
9
9
0
0
84
0
0
0
0
0
0
0
9
84
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
100
9
0
0
0
0
0
0
9
9
0
0
84
75
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
84
0
0
75
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
84
0
17
0
0
0
84
0
0
0
0
% R
% Ser:
0
0
75
84
9
0
59
0
0
0
9
9
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
0
0
0
0
9
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
9
9
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _