KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD4
All Species:
32.73
Human Site:
Y206
Identified Species:
65.45
UniProt:
Q9ULV1
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULV1
NP_036325.2
537
59881
Y206
N
C
V
L
K
C
G
Y
D
A
G
L
Y
S
R
Chimpanzee
Pan troglodytes
XP_001175326
537
59849
Y206
N
C
V
L
K
C
G
Y
D
A
G
L
Y
S
R
Rhesus Macaque
Macaca mulatta
XP_001103927
537
59890
Y206
N
C
V
L
K
C
G
Y
D
A
G
L
Y
S
R
Dog
Lupus familis
XP_848753
541
60627
Y210
N
C
V
L
K
C
G
Y
D
A
G
L
Y
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61088
537
60125
Y206
N
C
V
L
K
C
G
Y
D
A
G
L
Y
S
R
Rat
Rattus norvegicus
Q9QZH0
538
60336
Y207
N
C
V
L
K
C
G
Y
D
A
G
L
Y
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511743
486
54161
F167
H
S
R
S
A
K
E
F
T
D
V
W
M
A
V
Chicken
Gallus gallus
Q9IA05
525
58747
Y194
D
C
V
L
K
C
G
Y
D
A
G
L
Y
S
R
Frog
Xenopus laevis
Q9PT62
523
58722
Y192
N
C
V
L
K
C
G
Y
D
S
G
L
Y
N
R
Zebra Danio
Brachydanio rerio
XP_002664771
455
51006
T136
R
R
Q
A
K
V
F
T
D
V
W
M
A
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
C233
L
H
D
C
G
A
P
C
H
A
M
F
F
P
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788346
818
91850
D203
E
K
C
A
L
R
C
D
A
D
F
L
F
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.8
97.9
N.A.
97
97.2
N.A.
83.4
93.3
89.3
70.7
N.A.
35.6
N.A.
N.A.
39.4
Protein Similarity:
100
100
100
98.1
N.A.
98.1
98.1
N.A.
87.5
95.3
93.3
76.1
N.A.
52.5
N.A.
N.A.
50.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
93.3
86.6
13.3
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
100
20
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
9
9
0
0
9
67
0
0
9
9
0
% A
% Cys:
0
67
9
9
0
67
9
9
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
0
0
9
75
17
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
9
9
17
0
0
% F
% Gly:
0
0
0
0
9
0
67
0
0
0
67
0
0
0
0
% G
% His:
9
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
75
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
67
9
0
0
0
0
0
0
75
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
9
9
0
0
% M
% Asn:
59
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
9
9
9
0
0
9
0
0
0
0
0
0
0
0
67
% R
% Ser:
0
9
0
9
0
0
0
0
0
9
0
0
0
67
0
% S
% Thr:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% T
% Val:
0
0
67
0
0
9
0
0
0
9
9
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
67
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _