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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD4
All Species:
30.91
Human Site:
S183
Identified Species:
61.82
UniProt:
Q9ULV1
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULV1
NP_036325.2
537
59881
S183
Q
P
G
E
E
C
H
S
V
G
T
N
S
D
Q
Chimpanzee
Pan troglodytes
XP_001175326
537
59849
S183
Q
P
G
E
E
C
H
S
V
G
T
N
S
D
Q
Rhesus Macaque
Macaca mulatta
XP_001103927
537
59890
S183
Q
P
G
E
E
C
H
S
V
G
T
N
S
D
Q
Dog
Lupus familis
XP_848753
541
60627
S187
Q
P
G
E
E
C
H
S
V
G
T
N
S
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61088
537
60125
S183
Q
P
G
E
E
C
H
S
V
G
S
N
S
D
Q
Rat
Rattus norvegicus
Q9QZH0
538
60336
S184
Q
P
G
E
E
C
H
S
V
G
T
N
S
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511743
486
54161
K144
S
D
Q
Y
V
W
V
K
R
S
L
S
C
V
L
Chicken
Gallus gallus
Q9IA05
525
58747
S171
Q
P
G
E
E
C
H
S
M
G
S
N
S
D
Q
Frog
Xenopus laevis
Q9PT62
523
58722
S169
L
P
G
E
D
C
N
S
F
G
P
N
S
D
Q
Zebra Danio
Brachydanio rerio
XP_002664771
455
51006
R113
E
Q
Y
A
W
V
K
R
S
G
S
C
S
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
K210
F
V
C
P
V
Q
L
K
T
P
L
G
M
G
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788346
818
91850
C180
Q
E
P
G
E
P
D
C
Q
H
H
R
E
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.8
97.9
N.A.
97
97.2
N.A.
83.4
93.3
89.3
70.7
N.A.
35.6
N.A.
N.A.
39.4
Protein Similarity:
100
100
100
98.1
N.A.
98.1
98.1
N.A.
87.5
95.3
93.3
76.1
N.A.
52.5
N.A.
N.A.
50.1
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
0
86.6
66.6
20
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
80
33.3
N.A.
0
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
9
0
0
67
0
9
0
0
0
9
9
0
0
% C
% Asp:
0
9
0
0
9
0
9
0
0
0
0
0
0
67
0
% D
% Glu:
9
9
0
67
67
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
67
9
0
0
0
0
0
75
0
9
0
9
0
% G
% His:
0
0
0
0
0
0
59
0
0
9
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
17
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
0
9
0
0
0
17
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
0
67
0
0
0
% N
% Pro:
0
67
9
9
0
9
0
0
0
9
9
0
0
9
0
% P
% Gln:
67
9
9
0
0
9
0
0
9
0
0
0
0
0
84
% Q
% Arg:
0
0
0
0
0
0
0
9
9
0
0
9
0
0
0
% R
% Ser:
9
0
0
0
0
0
0
67
9
9
25
9
75
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
42
0
0
0
0
% T
% Val:
0
9
0
0
17
9
9
0
50
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _