KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO5B
All Species:
31.52
Human Site:
Y223
Identified Species:
69.33
UniProt:
Q9ULV0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULV0
NP_001073936
1849
213756
Y223
N
S
S
R
F
G
K
Y
I
Q
I
G
F
D
K
Chimpanzee
Pan troglodytes
XP_001170365
1848
214427
Y223
N
S
S
R
F
G
K
Y
I
E
I
G
F
D
K
Rhesus Macaque
Macaca mulatta
XP_001090434
1849
213576
Y223
N
S
S
R
F
G
K
Y
I
Q
I
G
F
D
K
Dog
Lupus familis
XP_537345
1850
213656
Y246
N
S
S
R
F
G
K
Y
I
Q
I
G
F
D
K
Cat
Felis silvestris
Mouse
Mus musculus
P21271
1818
210552
F223
N
S
S
R
F
G
K
F
I
E
I
G
F
D
K
Rat
Rattus norvegicus
P70569
1846
213702
Y223
N
S
S
R
F
G
K
Y
I
E
I
G
F
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q02440
1829
212364
Y223
N
S
S
R
F
G
K
Y
I
E
I
G
F
D
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001155104
1839
212863
Y223
N
S
S
R
F
G
K
Y
I
Q
I
G
F
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122188
1756
203360
F222
N
S
S
R
F
G
K
F
I
E
I
Q
F
N
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999655
1824
211646
Y222
N
S
S
R
F
G
K
Y
I
E
I
R
F
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19524
1574
180662
K175
A
G
K
T
V
S
A
K
Y
I
M
R
Y
F
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.6
97.1
89.8
N.A.
88.7
89.8
N.A.
N.A.
63
N.A.
72.1
N.A.
N.A.
41.7
N.A.
50.3
Protein Similarity:
100
79.4
98
94.3
N.A.
94.1
95.1
N.A.
N.A.
78.6
N.A.
83.9
N.A.
N.A.
60
N.A.
68.9
P-Site Identity:
100
93.3
100
100
N.A.
86.6
93.3
N.A.
N.A.
93.3
N.A.
93.3
N.A.
N.A.
73.3
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
93.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
73
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
55
0
0
0
0
0
% E
% Phe:
0
0
0
0
91
0
0
19
0
0
0
0
91
10
0
% F
% Gly:
0
10
0
0
0
91
0
0
0
0
0
73
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
91
10
91
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
91
10
0
0
0
0
0
0
73
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
91
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
37
0
10
0
0
0
% Q
% Arg:
0
0
0
91
0
0
0
0
0
0
0
19
0
0
19
% R
% Ser:
0
91
91
0
0
10
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
10
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _