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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYO5B All Species: 18.18
Human Site: S352 Identified Species: 40
UniProt: Q9ULV0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULV0 NP_001073936 1849 213756 S352 D G D S C S I S P Q D V Y L S
Chimpanzee Pan troglodytes XP_001170365 1848 214427 P352 A D S C T I P P K H E P L C I
Rhesus Macaque Macaca mulatta XP_001090434 1849 213576 S352 D G D S C S I S P Q D E H L S
Dog Lupus familis XP_537345 1850 213656 S375 D G D S C S V S P Q D E H L N
Cat Felis silvestris
Mouse Mus musculus P21271 1818 210552 S352 D G D S C S I S P Q D E H L S
Rat Rattus norvegicus P70569 1846 213702 S352 D G D S C S I S P Q D E H L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q02440 1829 212364 P351 D S D S C A I P P K H D P L T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001155104 1839 212863 N352 D G E S C H I N R D D T H L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122188 1756 203360 S349 N Q T L N N E S D T E T S Y I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999655 1824 211646 V351 H E S C K I E V E S E S L P I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P19524 1574 180662 D302 F Y M N Q G G D T K I N G I D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.6 97.1 89.8 N.A. 88.7 89.8 N.A. N.A. 63 N.A. 72.1 N.A. N.A. 41.7 N.A. 50.3
Protein Similarity: 100 79.4 98 94.3 N.A. 94.1 95.1 N.A. N.A. 78.6 N.A. 83.9 N.A. N.A. 60 N.A. 68.9
P-Site Identity: 100 0 86.6 73.3 N.A. 86.6 86.6 N.A. N.A. 46.6 N.A. 46.6 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 6.6 93.3 93.3 N.A. 93.3 93.3 N.A. N.A. 66.6 N.A. 66.6 N.A. N.A. 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 19 64 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 64 10 55 0 0 0 0 10 10 10 55 10 0 0 10 % D
% Glu: 0 10 10 0 0 0 19 0 10 0 28 37 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 55 0 0 0 10 10 0 0 0 0 0 10 0 0 % G
% His: 10 0 0 0 0 10 0 0 0 10 10 0 46 0 10 % H
% Ile: 0 0 0 0 0 19 55 0 0 0 10 0 0 10 28 % I
% Lys: 0 0 0 0 10 0 0 0 10 19 0 0 0 0 0 % K
% Leu: 0 0 0 10 0 0 0 0 0 0 0 0 19 64 0 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 10 10 10 0 10 0 0 0 10 0 0 10 % N
% Pro: 0 0 0 0 0 0 10 19 55 0 0 10 10 10 0 % P
% Gln: 0 10 0 0 10 0 0 0 0 46 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 10 19 64 0 46 0 55 0 10 0 10 10 0 37 % S
% Thr: 0 0 10 0 10 0 0 0 10 10 0 19 0 0 10 % T
% Val: 0 0 0 0 0 0 10 10 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _