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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO5B
All Species:
15.76
Human Site:
S1290
Identified Species:
34.67
UniProt:
Q9ULV0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULV0
NP_001073936
1849
213756
S1290
P
N
I
N
A
R
S
S
W
P
N
S
E
K
H
Chimpanzee
Pan troglodytes
XP_001170365
1848
214427
S1290
T
Q
L
N
W
R
Q
S
L
S
N
V
Q
K
M
Rhesus Macaque
Macaca mulatta
XP_001090434
1849
213576
S1291
P
N
I
N
A
R
S
S
W
P
N
S
E
K
H
Dog
Lupus familis
XP_537345
1850
213656
G1306
A
D
Q
R
R
L
T
G
R
S
T
E
P
S
I
Cat
Felis silvestris
Mouse
Mus musculus
P21271
1818
210552
S1286
P
N
I
N
A
R
T
S
W
P
N
S
E
K
H
Rat
Rattus norvegicus
P70569
1846
213702
S1288
P
N
I
N
A
R
T
S
W
P
N
S
E
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q02440
1829
212364
K1284
Q
K
E
A
I
Q
P
K
E
D
K
N
T
M
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001155104
1839
212863
N1282
N
L
N
H
I
N
S
N
D
V
S
E
W
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122188
1756
203360
N1235
G
V
T
G
A
Q
Q
N
L
M
G
Q
F
D
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999655
1824
211646
R1251
T
D
L
V
N
R
R
R
Q
W
A
L
Q
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19524
1574
180662
Q1081
K
E
E
I
A
R
L
Q
T
A
M
S
L
G
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.6
97.1
89.8
N.A.
88.7
89.8
N.A.
N.A.
63
N.A.
72.1
N.A.
N.A.
41.7
N.A.
50.3
Protein Similarity:
100
79.4
98
94.3
N.A.
94.1
95.1
N.A.
N.A.
78.6
N.A.
83.9
N.A.
N.A.
60
N.A.
68.9
P-Site Identity:
100
33.3
100
0
N.A.
93.3
93.3
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
46.6
100
13.3
N.A.
100
100
N.A.
N.A.
13.3
N.A.
26.6
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
55
0
0
0
0
10
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
0
0
0
0
10
10
0
0
0
10
10
% D
% Glu:
0
10
19
0
0
0
0
0
10
0
0
19
37
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
0
0
10
0
0
0
10
0
0
10
0
0
10
10
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
37
% H
% Ile:
0
0
37
10
19
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
10
10
0
0
0
0
0
10
0
0
10
0
0
46
0
% K
% Leu:
0
10
19
0
0
10
10
0
19
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
10
0
0
10
10
% M
% Asn:
10
37
10
46
10
10
0
19
0
0
46
10
0
0
0
% N
% Pro:
37
0
0
0
0
0
10
0
0
37
0
0
10
0
0
% P
% Gln:
10
10
10
0
0
19
19
10
10
0
0
10
19
0
0
% Q
% Arg:
0
0
0
10
10
64
10
10
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
28
46
0
19
10
46
0
10
0
% S
% Thr:
19
0
10
0
0
0
28
0
10
0
10
0
10
10
19
% T
% Val:
0
10
0
10
0
0
0
0
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
37
10
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _