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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHH1
All Species:
1.52
Human Site:
T288
Identified Species:
4.17
UniProt:
Q9ULM0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULM0
NP_065766.1
1364
151232
T288
S
W
G
E
G
L
V
T
A
Q
R
G
M
L
P
Chimpanzee
Pan troglodytes
XP_525888
1493
168136
S287
G
A
P
V
S
D
W
S
S
D
E
E
D
G
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537487
1476
163215
A401
W
G
E
G
L
V
I
A
Q
G
G
T
L
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80TI1
1356
150890
A287
Y
R
E
S
L
V
T
A
Q
G
G
T
F
P
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516496
937
103987
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q00IB7
1433
160027
S294
A
S
D
R
D
H
S
S
D
E
L
N
S
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W5D0
1820
198623
I554
T
A
H
D
Y
A
E
I
Y
T
P
S
C
E
K
Honey Bee
Apis mellifera
XP_001120273
1571
174100
K333
M
M
E
E
R
L
V
K
G
E
Y
C
L
S
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782886
2057
229359
Q379
M
I
A
Q
E
K
A
Q
E
R
T
K
P
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49
N.A.
80.5
N.A.
83.5
N.A.
N.A.
43.1
N.A.
N.A.
56.7
N.A.
30.7
35.6
N.A.
30.7
Protein Similarity:
100
65.5
N.A.
84.1
N.A.
88.8
N.A.
N.A.
54.1
N.A.
N.A.
71.8
N.A.
46.4
51.5
N.A.
43.4
P-Site Identity:
100
0
N.A.
0
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
0
N.A.
0
20
N.A.
0
P-Site Similarity:
100
13.3
N.A.
20
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
20
N.A.
13.3
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
23
12
0
0
12
12
23
12
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
12
12
0
0
% C
% Asp:
0
0
12
12
12
12
0
0
12
12
0
0
12
0
0
% D
% Glu:
0
0
34
23
12
0
12
0
12
23
12
12
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% F
% Gly:
12
12
12
12
12
0
0
0
12
23
23
12
0
12
23
% G
% His:
0
0
12
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
12
12
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
0
12
0
0
0
12
0
12
12
% K
% Leu:
0
0
0
0
23
23
0
0
0
0
12
0
23
12
0
% L
% Met:
23
12
0
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
12
0
12
34
12
% P
% Gln:
0
0
0
12
0
0
0
12
23
12
0
0
0
0
0
% Q
% Arg:
0
12
0
12
12
0
0
0
0
12
12
0
0
0
12
% R
% Ser:
12
12
0
12
12
0
12
23
12
0
0
12
12
12
12
% S
% Thr:
12
0
0
0
0
0
12
12
0
12
12
23
0
0
12
% T
% Val:
0
0
0
12
0
23
23
0
0
0
0
0
0
0
0
% V
% Trp:
12
12
0
0
0
0
12
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
12
0
0
0
12
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _