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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLEKHH1 All Species: 11.52
Human Site: S84 Identified Species: 31.67
UniProt: Q9ULM0 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULM0 NP_065766.1 1364 151232 S84 K N V D S E G S L H R K Y Q E
Chimpanzee Pan troglodytes XP_525888 1493 168136 R83 Q T S E S E T R L Y N K C Q D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537487 1476 163215 S197 K N V D L G G S L H Q K Y Q E
Cat Felis silvestris
Mouse Mus musculus Q80TI1 1356 150890 T83 K S V D S T G T L H Q K Y Q E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516496 937 103987
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q00IB7 1433 160027 S90 Q P S E T E N S L Y R S Y Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W5D0 1820 198623 A350 S H Q A S G G A T A G A A G S
Honey Bee Apis mellifera XP_001120273 1571 174100 A111 A N N N H A A A I Q G P P G T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782886 2057 229359 G117 K R I I T L E G L C R E K E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49 N.A. 80.5 N.A. 83.5 N.A. N.A. 43.1 N.A. N.A. 56.7 N.A. 30.7 35.6 N.A. 30.7
Protein Similarity: 100 65.5 N.A. 84.1 N.A. 88.8 N.A. N.A. 54.1 N.A. N.A. 71.8 N.A. 46.4 51.5 N.A. 43.4
P-Site Identity: 100 33.3 N.A. 80 N.A. 73.3 N.A. N.A. 0 N.A. N.A. 46.6 N.A. 13.3 6.6 N.A. 20
P-Site Similarity: 100 60 N.A. 86.6 N.A. 93.3 N.A. N.A. 0 N.A. N.A. 73.3 N.A. 26.6 26.6 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 12 0 12 12 23 0 12 0 12 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 12 0 0 12 0 0 % C
% Asp: 0 0 0 34 0 0 0 0 0 0 0 0 0 0 23 % D
% Glu: 0 0 0 23 0 34 12 0 0 0 0 12 0 12 45 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 23 45 12 0 0 23 0 0 23 0 % G
% His: 0 12 0 0 12 0 0 0 0 34 0 0 0 0 0 % H
% Ile: 0 0 12 12 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 45 0 0 0 0 0 0 0 0 0 0 45 12 0 0 % K
% Leu: 0 0 0 0 12 12 0 0 67 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 34 12 12 0 0 12 0 0 0 12 0 0 0 0 % N
% Pro: 0 12 0 0 0 0 0 0 0 0 0 12 12 0 0 % P
% Gln: 23 0 12 0 0 0 0 0 0 12 23 0 0 56 0 % Q
% Arg: 0 12 0 0 0 0 0 12 0 0 34 0 0 0 0 % R
% Ser: 12 12 23 0 45 0 0 34 0 0 0 12 0 0 12 % S
% Thr: 0 12 0 0 23 12 12 12 12 0 0 0 0 0 12 % T
% Val: 0 0 34 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 23 0 0 45 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _