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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHH1
All Species:
4.85
Human Site:
S439
Identified Species:
13.33
UniProt:
Q9ULM0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULM0
NP_065766.1
1364
151232
S439
G
M
R
L
S
D
M
S
P
R
S
N
T
A
C
Chimpanzee
Pan troglodytes
XP_525888
1493
168136
M564
V
A
K
S
G
I
R
M
S
E
A
F
N
M
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537487
1476
163215
S551
G
M
R
L
S
D
A
S
S
R
T
N
V
T
C
Cat
Felis silvestris
Mouse
Mus musculus
Q80TI1
1356
150890
L433
M
A
T
S
G
M
Q
L
S
E
V
S
S
R
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516496
937
103987
P66
E
D
G
S
A
P
R
P
G
P
R
T
A
G
F
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q00IB7
1433
160027
S504
A
K
L
G
M
R
V
S
E
A
C
L
G
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W5D0
1820
198623
K770
S
S
S
L
S
P
A
K
R
S
G
S
E
S
P
Honey Bee
Apis mellifera
XP_001120273
1571
174100
S571
H
N
L
T
A
H
N
S
Q
G
Y
C
D
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782886
2057
229359
P688
L
T
L
I
R
S
T
P
F
T
G
E
S
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49
N.A.
80.5
N.A.
83.5
N.A.
N.A.
43.1
N.A.
N.A.
56.7
N.A.
30.7
35.6
N.A.
30.7
Protein Similarity:
100
65.5
N.A.
84.1
N.A.
88.8
N.A.
N.A.
54.1
N.A.
N.A.
71.8
N.A.
46.4
51.5
N.A.
43.4
P-Site Identity:
100
0
N.A.
66.6
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
13.3
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
13.3
N.A.
73.3
N.A.
13.3
N.A.
N.A.
6.6
N.A.
N.A.
20
N.A.
26.6
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
23
0
0
23
0
23
0
0
12
12
0
12
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
23
% C
% Asp:
0
12
0
0
0
23
0
0
0
0
0
0
12
0
12
% D
% Glu:
12
0
0
0
0
0
0
0
12
23
0
12
12
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
0
12
0
0
12
% F
% Gly:
23
0
12
12
23
0
0
0
12
12
23
0
12
12
0
% G
% His:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
12
0
0
0
0
0
0
0
12
0
% I
% Lys:
0
12
12
0
0
0
0
12
0
0
0
0
0
0
12
% K
% Leu:
12
0
34
34
0
0
0
12
0
0
0
12
0
0
0
% L
% Met:
12
23
0
0
12
12
12
12
0
0
0
0
0
12
0
% M
% Asn:
0
12
0
0
0
0
12
0
0
0
0
23
12
0
0
% N
% Pro:
0
0
0
0
0
23
0
23
12
12
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
12
0
12
0
0
0
0
0
0
% Q
% Arg:
0
0
23
0
12
12
23
0
12
23
12
0
0
12
12
% R
% Ser:
12
12
12
34
34
12
0
45
34
12
12
23
23
23
12
% S
% Thr:
0
12
12
12
0
0
12
0
0
12
12
12
12
12
0
% T
% Val:
12
0
0
0
0
0
12
0
0
0
12
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _