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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNH3 All Species: 31.21
Human Site: T53 Identified Species: 76.3
UniProt: Q9ULD8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULD8 NP_036416.1 1083 117129 T53 S D G F C D L T G F S R A E V
Chimpanzee Pan troglodytes XP_509046 1083 117183 T53 S D G F C D L T G F S R A E V
Rhesus Macaque Macaca mulatta XP_001109598 1083 117285 T53 S D G F C D L T G F S R A E V
Dog Lupus familis XP_543682 1116 119872 T81 S D G F C D L T G F S R A E V
Cat Felis silvestris
Mouse Mus musculus Q9WVJ0 1087 117519 T53 S D G F C D L T G F S R A E V
Rat Rattus norvegicus O89047 1087 117562 T53 S D G F C D L T G F S R A E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508200 1155 129668 A103 S D G F C E L A G F T R T E V
Chicken Gallus gallus Q9PT84 526 59775
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919436 1190 130720 T51 S D G F C E L T G Y A R A E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02280 1174 126352 S54 N E S F C K I S G Y N R A E V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.4 89.7 N.A. 95.4 95.5 N.A. 45.7 22.4 N.A. 47.6 N.A. 30.8 N.A. N.A. N.A.
Protein Similarity: 100 99.7 99.6 91.7 N.A. 96.4 96.5 N.A. 60 32.7 N.A. 60 N.A. 48.8 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 73.3 0 N.A. 73.3 N.A. 46.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 0 N.A. 100 N.A. 86.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 10 0 80 0 0 % A
% Cys: 0 0 0 0 90 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 80 0 0 0 60 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 20 0 0 0 0 0 0 0 90 0 % E
% Phe: 0 0 0 90 0 0 0 0 0 70 0 0 0 0 0 % F
% Gly: 0 0 80 0 0 0 0 0 90 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 80 0 0 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 90 0 0 0 % R
% Ser: 80 0 10 0 0 0 0 10 0 0 60 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 70 0 0 10 0 10 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _