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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF2C1
All Species:
40
Human Site:
S615
Identified Species:
73.33
UniProt:
Q9UL18
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UL18
NP_036331.1
857
97214
S615
S
I
T
A
V
V
G
S
M
D
A
H
P
S
R
Chimpanzee
Pan troglodytes
XP_001167349
817
92830
S575
S
I
T
A
V
V
G
S
M
D
A
H
P
S
R
Rhesus Macaque
Macaca mulatta
XP_001100725
1053
117937
S811
S
I
A
A
V
V
G
S
M
D
A
H
P
N
R
Dog
Lupus familis
XP_532563
1037
115859
S795
S
I
T
A
V
V
G
S
M
D
A
H
P
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CJG1
857
97083
S615
S
I
T
A
V
V
G
S
M
D
A
H
P
S
R
Rat
Rattus norvegicus
Q9QZ81
860
97300
S618
S
I
A
A
V
V
G
S
M
D
A
H
P
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510209
1055
118422
S813
S
I
T
A
V
V
G
S
M
D
A
H
P
S
R
Chicken
Gallus gallus
Q5ZLG4
860
97253
S618
S
I
A
A
V
V
G
S
M
D
A
H
P
S
R
Frog
Xenopus laevis
Q6DCX2
862
97626
S620
S
I
A
A
V
V
G
S
M
D
A
H
P
N
R
Zebra Danio
Brachydanio rerio
A3KPK0
860
97313
S618
S
I
A
A
V
V
G
S
M
D
A
H
P
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUQ5
1214
136831
S970
G
A
D
V
T
H
P
S
P
D
Q
R
E
I
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34681
1040
115397
N765
S
V
A
A
I
V
A
N
V
D
L
L
P
Q
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04379
1048
116172
C794
T
K
Y
A
G
L
V
C
A
Q
A
H
R
Q
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
66.8
82.6
N.A.
99.5
82.3
N.A.
75.2
84.5
82
84.7
N.A.
23.2
N.A.
32.6
N.A.
Protein Similarity:
100
94.1
74.8
82.6
N.A.
99.7
91.2
N.A.
76.7
91.6
90.5
92
N.A.
37.1
N.A.
51.1
N.A.
P-Site Identity:
100
100
86.6
100
N.A.
100
86.6
N.A.
100
93.3
86.6
93.3
N.A.
13.3
N.A.
33.3
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
93.3
N.A.
100
93.3
93.3
93.3
N.A.
13.3
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
47
93
0
0
8
0
8
0
85
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
93
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
77
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
85
0
0
0
% H
% Ile:
0
77
0
0
8
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
77
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
24
0
% N
% Pro:
0
0
0
0
0
0
8
0
8
0
0
0
85
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
8
0
0
16
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
77
% R
% Ser:
85
0
0
0
0
0
0
85
0
0
0
0
0
54
8
% S
% Thr:
8
0
39
0
8
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
8
77
85
8
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _