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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF2C1
All Species:
34.55
Human Site:
S288
Identified Species:
63.33
UniProt:
Q9UL18
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UL18
NP_036331.1
857
97214
S288
N
V
T
R
R
P
A
S
H
Q
T
F
P
L
Q
Chimpanzee
Pan troglodytes
XP_001167349
817
92830
V266
G
Q
T
V
E
C
T
V
A
Q
Y
F
K
Q
K
Rhesus Macaque
Macaca mulatta
XP_001100725
1053
117937
S482
N
V
T
R
R
P
A
S
H
Q
T
F
P
L
Q
Dog
Lupus familis
XP_532563
1037
115859
S468
N
V
T
R
R
P
A
S
H
Q
T
F
P
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CJG1
857
97083
S288
N
V
T
R
R
P
A
S
H
Q
T
F
P
L
Q
Rat
Rattus norvegicus
Q9QZ81
860
97300
S291
N
V
T
R
R
P
A
S
H
Q
T
F
P
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510209
1055
118422
S486
S
L
S
L
Y
L
F
S
P
S
S
F
P
L
Q
Chicken
Gallus gallus
Q5ZLG4
860
97253
S291
N
V
T
R
R
P
A
S
H
Q
T
F
P
L
Q
Frog
Xenopus laevis
Q6DCX2
862
97626
S293
N
V
T
R
R
P
A
S
H
Q
T
F
P
L
Q
Zebra Danio
Brachydanio rerio
A3KPK0
860
97313
S291
N
V
T
R
R
P
A
S
H
Q
T
F
P
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUQ5
1214
136831
L659
R
V
Y
R
V
N
G
L
S
R
A
P
A
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34681
1040
115397
A428
V
N
S
L
Q
L
P
A
D
K
L
M
F
Q
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04379
1048
116172
R446
G
L
T
A
V
A
T
R
E
L
T
F
P
V
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
66.8
82.6
N.A.
99.5
82.3
N.A.
75.2
84.5
82
84.7
N.A.
23.2
N.A.
32.6
N.A.
Protein Similarity:
100
94.1
74.8
82.6
N.A.
99.7
91.2
N.A.
76.7
91.6
90.5
92
N.A.
37.1
N.A.
51.1
N.A.
P-Site Identity:
100
20
100
100
N.A.
100
100
N.A.
33.3
100
100
100
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
60
100
100
100
N.A.
20
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
62
8
8
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
85
8
0
0
% F
% Gly:
16
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
62
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
8
% K
% Leu:
0
16
0
16
0
16
0
8
0
8
8
0
0
70
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
62
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
62
8
0
8
0
0
8
77
0
0
% P
% Gln:
0
8
0
0
8
0
0
0
0
70
0
0
0
16
70
% Q
% Arg:
8
0
0
70
62
0
0
8
0
8
0
0
0
0
0
% R
% Ser:
8
0
16
0
0
0
0
70
8
8
8
0
0
8
8
% S
% Thr:
0
0
77
0
0
0
16
0
0
0
70
0
0
0
0
% T
% Val:
8
70
0
8
16
0
0
8
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _